caa a22 4500 475782429 CHVBK 20180406123648.0 cr unu---uuuuu 170329e20000901xx s 000 0 eng 10.1023/A:1008924102096 doi (NATIONALLICENCE)springer-10.1023/A:1008924102096 Formation of bioactive functionally graded structure on Ti-6Al-4V alloy by chemical surface treatment [Elektronische Daten] [H.-M. Kim, H. Takadama, F. Miyaji, T. Kokubo, S. Nishiguchi, T. Nakamura] An Al- and V-free sodium titanate hydrogel layer with a graded structure where the sodium titanate gradually decreases toward the interior, was formed on the surface of Ti-6Al-4V alloy, when the alloy was exposed to 5M NaOH solution at 60 °C for 24 h. This gel layer was transformed into an amorphous sodium titanate layer without giving considerable change in the graded structure, except a little increase in the depth of the oxygen distribution by a heat treatment at 600 °C for 1 h. The sodium titanate layer formed Ti-OH groups on its surface by exchanging its Na+ ion with H3O+ ion in simulated body fluid when soaked in the fluid, and thus formed Ti-OH groups induced the apatite nucleation. The apatite layer also formed a graded structure toward the substrate. The strong bond of the apatite layer to the substrate was attributed to this graded structure. Kluwer Academic Publishers, 2000 Kim H.-M Department of Material Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606-8501, Kyoto, Japan aut Takadama H. Department of Material Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606-8501, Kyoto, Japan aut Miyaji F. Department of Material Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606-8501, Kyoto, Japan aut Kokubo T. Department of Material Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606-8501, Kyoto, Japan aut Nishiguchi S. Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, Sakyo-ku, 606-8506, Kyoto, Japan aut Nakamura T. Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, Sakyo-ku, 606-8506, Kyoto, Japan aut Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/9(2000-09-01), 555-559 0957-4530 11:9<555 2000 11 10856 https://doi.org/10.1023/A:1008924102096 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1008924102096 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kim H.-M Department of Material Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606-8501, Kyoto, Japan aut NATIONALLICENCE 700 1- Takadama H. Department of Material Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606-8501, Kyoto, Japan aut NATIONALLICENCE 700 1- Miyaji F. Department of Material Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606-8501, Kyoto, Japan aut NATIONALLICENCE 700 1- Kokubo T. Department of Material Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606-8501, Kyoto, Japan aut NATIONALLICENCE 700 1- Nishiguchi S. Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, Sakyo-ku, 606-8506, Kyoto, Japan aut NATIONALLICENCE 700 1- Nakamura T. Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, Sakyo-ku, 606-8506, Kyoto, Japan aut NATIONALLICENCE 773 0- Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/9(2000-09-01), 555-559 0957-4530 11:9<555 2000 11 10856 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer