caa a22 4500 475782534 CHVBK 20180406123648.0 cr unu---uuuuu 170329e20000701xx s 000 0 eng 10.1023/A:1008935924847 doi (NATIONALLICENCE)springer-10.1023/A:1008935924847 Composition and structure of apatite formed on organic polymer in simulated body fluid with a high content of carbonate ion [Elektronische Daten] [H.-M. Kim, K. Kishimoto, F. Miyaji, T. Kokubo, T. Yao, Y. Suetsugu, J. Tanaka, T. Nakamura] Apatite layer was formed on polyethyleneterephthalate (PET) substrate by the following biomimetic process. The PET substrate was placed on granular particles of a CaO, SiO2-based glass in simulated body fluid (SBF) with ion concentrations nearly equal to those of human blood plasma to form apatite nuclei on their surfaces. The apatite nuclei was then grown into a continuous layer by subsequently soaking the substrate in SBF under air or CO2 atmosphere in which CO2 partial pressure in the ambient was adjusted to 14.8 kPa to increase the content of carbonate ion to a level nearly equal to that of blood plasma. The increase in the content of carbonate ions in SBF changed the Ca/P atomic ratio of the apatite from 1.51 to 1.63, content of CO3 2- ions from 2.64 to 4.56 wt %, and lattice constants a from 94.32 to 94.23 nm and c from 68.70 to 68.83 nm, respectively. The Ca/P ratio and lattice constants of the apatite formed in SBF under CO2 atmosphere were approximately identical to those of bone apatite, i.e. Ca/P atomic ratio 1.65, content of CO3 2- ion 5.80 wt % and lattice constants a 94.20 and c 68.80 nm. This indicates that an apatite with composition and structure nearly identical to those of bone apatite can be produced in SBF by adjusting its ion concentrations including the content of carbonate ions to be equal to those of blood plasma. Kluwer Academic Publishers, 2000 Kim H.-M aut Kishimoto K. aut Miyaji F. aut Kokubo T. aut Yao T. aut Suetsugu Y. aut Tanaka J. aut Nakamura T. E-mail: kim@sung7.kuic.kyoto-u.ac.jp aut Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/7(2000-07-01), 421-426 0957-4530 11:7<421 2000 11 10856 https://doi.org/10.1023/A:1008935924847 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1008935924847 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kim H.-M aut NATIONALLICENCE 700 1- Kishimoto K. aut NATIONALLICENCE 700 1- Miyaji F. aut NATIONALLICENCE 700 1- Kokubo T. aut NATIONALLICENCE 700 1- Yao T. aut NATIONALLICENCE 700 1- Suetsugu Y. aut NATIONALLICENCE 700 1- Tanaka J. aut NATIONALLICENCE 700 1- Nakamura T. E-mail: kim@sung7.kuic.kyoto-u.ac.jp aut NATIONALLICENCE 773 0- Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/7(2000-07-01), 421-426 0957-4530 11:7<421 2000 11 10856 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer