caa a22 4500 475782682 CHVBK 20180406123649.0 cr unu---uuuuu 170329e20001201xx s 000 0 eng 10.1023/A:1008961730929 doi (NATIONALLICENCE)springer-10.1023/A:1008961730929 β-Chitin-based wound dressing containing silver sulfurdiazine [Elektronische Daten] [Young Lee, Seong Kim, Moon Park, Kang Song, Yong Sung, In Kang] Physical and biological properties of some wound dressing materials based on β-chitin were studied. Water vapor transmission rates (WVTR), oxygen permeabilities and biodegradation kinetics were examined for film-type samples. WVTR of samples was in the range 2400-2800 g/m2/day. However, oxygen permeabilities of the samples were relatively low. To improve oxygen permeabilities, porous sponge-type wound dressing materials were prepared. In addition, these sponge-type samples contained antimicrobial agents, silver sulfadiazine (AgSD), in order to prevent bacteria infection on a wound surface. Anti-microbacterial tests on agar plate were carried out to confirm the bactericidal capacity of present materials. These materials impregnating AgSD had the complete bactericidal capacity against pseudomonas aeruginosa up to 7 days. Finally, a wound healing effect of β-chitin-based semi-interpenetrating polymer networks was evaluated from the animal test using the wistar rat in vivo. Histological studies confirm the proliferation of fibroblasts in the wound bed and a distinct reduction in infectious cells. Kluwer Academic Publishers, 2000 Lee Young School of Chemical Engineering, College of Engineering, Hanyang University, 133-791, Seoul, Korea aut Kim Seong School of Chemical Engineering, College of Engineering, Hanyang University, 133-791, Seoul, Korea aut Park Moon Department of Pathology, College of Medicine, Hanyang University, 133-791, Seoul, Korea aut Song Kang Department of Pathology, College of Medicine, Hanyang University, 133-791, Seoul, Korea aut Sung Yong Department of Chemistry, College of Natural Sciences, Dongguk University, 100-715, Seoul, Korea aut Kang In Department of Polymer Science, College of Engineering, Kyungpook National University, 702-701, Taegu, Korea aut Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/12(2000-12-01), 817-823 0957-4530 11:12<817 2000 11 10856 https://doi.org/10.1023/A:1008961730929 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1008961730929 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lee Young School of Chemical Engineering, College of Engineering, Hanyang University, 133-791, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Seong School of Chemical Engineering, College of Engineering, Hanyang University, 133-791, Seoul, Korea aut NATIONALLICENCE 700 1- Park Moon Department of Pathology, College of Medicine, Hanyang University, 133-791, Seoul, Korea aut NATIONALLICENCE 700 1- Song Kang Department of Pathology, College of Medicine, Hanyang University, 133-791, Seoul, Korea aut NATIONALLICENCE 700 1- Sung Yong Department of Chemistry, College of Natural Sciences, Dongguk University, 100-715, Seoul, Korea aut NATIONALLICENCE 700 1- Kang In Department of Polymer Science, College of Engineering, Kyungpook National University, 702-701, Taegu, Korea aut NATIONALLICENCE 773 0- Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/12(2000-12-01), 817-823 0957-4530 11:12<817 2000 11 10856 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer