caa a22 4500 47578281X CHVBK 20180406123649.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1023/A:1008949527695 doi (NATIONALLICENCE)springer-10.1023/A:1008949527695 Development of soluble glasses for biomedical use Part I: In vitro solubility measurement [Elektronische Daten] [K. Franks, I. Abrahams, J. Knowles] In this study soluble glasses have been developed for biomedical applications containing P2O5 as a network former and CaO and Na2O as modifiers. This study shows that as expected, the glasses have an inverse exponential relationship between solubility and CaO content. Furthermore, there is evidence for compositional related non-linearity in the dissolution of the glasses with time. This is thought to be due to either layer formation on the glass surface hindering ion diffusion, ion exchange process or change of ionic strength of the solution. Bioactivity of these glasses is indicated by the formation of a brushite precipitate, a precursor to apatite formation. Further evidence for bioactivity is also presented in the second part of this paper. Kluwer Academic Publishers, 2000 Franks K. Department of Biomaterials, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut Abrahams I. Queen Mary and Westfield College, Mile End Road, E1 4NS, London, UK aut Knowles J. Department of Biomaterials, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/10(2000-10-01), 609-614 0957-4530 11:10<609 2000 11 10856 https://doi.org/10.1023/A:1008949527695 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1008949527695 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Franks K. Department of Biomaterials, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut NATIONALLICENCE 700 1- Abrahams I. Queen Mary and Westfield College, Mile End Road, E1 4NS, London, UK aut NATIONALLICENCE 700 1- Knowles J. Department of Biomaterials, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut NATIONALLICENCE 773 0- Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/10(2000-10-01), 609-614 0957-4530 11:10<609 2000 11 10856 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer