caa a22 4500 475783026 CHVBK 20180406123650.0 cr unu---uuuuu 170329e20000801xx s 000 0 eng 10.1023/A:1013057724268 doi (NATIONALLICENCE)springer-10.1023/A:1013057724268 Mechanical properties of hydroxyapatite reinforced poly(ethylmethacrylate) bone cement after immersion in a physiological solution: influence of a silane coupling agent [Elektronische Daten] [E. Harper, M. Braden, W. Bonfield*] PEMA-based bone cement has previously been shown to possess many advantages over traditional PMMA cements. One of these is the option of adding up to 40 wt % HA without a decrease in static mechanical strength, thus providing the potential for enhanced bioactivity. Bone cement, in vivo, is subjected to an aqueous environment and therefore, it is important to understand the influence of this upon the mechanical integrity of experimental cements. In this current investigation the static and dynamic properties of PEMA cement, with and without 30 wt % untreated and silanated HA, were examined after periods of immersion in Ringer's solution. A commercial PMMA cement was also tested in a similar manner. Relatively small changes in static mechanical properties were observed after 12 weeks storage for the PEMA cements, the largest change being for the PEMA cement reinforced with silanated HA. The PMMA cement exhibited the largest change in static strength with a decrease of 16.6%. In contrast to these results, the fatigue properties of the PEMA cements were found to decrease significantly after storage in Ringer's solution, again with the largest changes to the PEMA cement reinforced with silanated HA. This effect was attributed to the reduction in efficiency of the silane coupling agent in the presence of water. The fatigue resistance of the PMMA cement was not reduced after immersion in a saline environment. Kluwer Academic Publishers, 2000 Harper E. IRC in Biomedical Materials, Queen Mary and Westfield College, Mile End Road, E1 4NS, London, UK aut Braden M. IRC in Biomedical Materials, Queen Mary and Westfield College, Mile End Road, E1 4NS, London, UK aut Bonfield* W. IRC in Biomedical Materials, Queen Mary and Westfield College, Mile End Road, E1 4NS, London, UK aut Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/8(2000-08-01), 491-497 0957-4530 11:8<491 2000 11 10856 https://doi.org/10.1023/A:1013057724268 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1013057724268 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Harper E. IRC in Biomedical Materials, Queen Mary and Westfield College, Mile End Road, E1 4NS, London, UK aut NATIONALLICENCE 700 1- Braden M. IRC in Biomedical Materials, Queen Mary and Westfield College, Mile End Road, E1 4NS, London, UK aut NATIONALLICENCE 700 1- Bonfield* W. IRC in Biomedical Materials, Queen Mary and Westfield College, Mile End Road, E1 4NS, London, UK aut NATIONALLICENCE 773 0- Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/8(2000-08-01), 491-497 0957-4530 11:8<491 2000 11 10856 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer