caa a22 4500 475783182 CHVBK 20180406123650.0 cr unu---uuuuu 170329e20000201xx s 000 0 eng 10.1023/A:1008997118576 doi (NATIONALLICENCE)springer-10.1023/A:1008997118576 Effect of several additives and their admixtures on the physico-chemical properties of a calcium phosphate cement [Elektronische Daten] [M. Bohner, H. Merkle, P. Landuyt, G. Trophardy, J. Lemaitre] Combinations of citrate (C6H5O 7 3-− ), pyrophosphate (P2O 7 4− ) and sulfate (SO 4 2− ) ions were used to modify the physico-chemical properties of a calcium phosphate cement (CPC) composed of β-tricalcium phosphate (β-TCP) and phosphoric acid (PA) solution. The results obtained with only one additive at a time are similar to those previously published. New facts are: the positive effect of C6H5O 7 3− ions on cement failure strain and their negative effect on cement pH. The position of the setting time maximum measured at an SO 4 2− concentration of 0.09 M was not displaced by the addition of C6H5O 7 3− and P2O 7 4− ions. However, the effect of SO 4 2− ions on the setting time was depressed by C6H5O 7 3− ions. Moreover, no increase in tensile strength was observed when increasing amounts of SO 4 2− were added into a C6H5O 7 3− -containing cement. The latter results suggest a competitive effect of C6H5O 7 3− and SO 4 2− on setting time and tensile strength. Anhydrous dicalcium phosphate (DCP; CaHPO4) appeared in cement samples dried just after setting, but not in cement samples incubated for 24 h in deionized water before the drying step. It is believed that the setting reaction is stopped by the drying step, leaving a low internal pH in the sample, hence providing favorable conditions for the transformation of dicalcium phosphate dihydrate (DCPD) into DCP. Interestingly, even though C6H5O 7 3− ions dramatically lowered the equilibrium pH of the cement with 5 ml of deionized water, they still prevented the occurrence of the transformation of DCPD into DCP. Kluwer Academic Publishers, 2000 Bohner M. Pharmacy Department, Swiss Federal Institute of Technology of Zurich (ETHZ), Winterthurerstrasse 190, 8057, Zurich, Switzerland aut Merkle H. Pharmacy Department, Swiss Federal Institute of Technology of Zurich (ETHZ), Winterthurerstrasse 190, 8057, Zurich, Switzerland aut Landuyt P. Laboratory of Powder Technology, DMX, Swiss Federal Institute of Technology of Lausanne (EPFL), 1015, Lausanne, Switzerland aut Trophardy G. Laboratory of Powder Technology, DMX, Swiss Federal Institute of Technology of Lausanne (EPFL), 1015, Lausanne, Switzerland aut Lemaitre J. Laboratory of Powder Technology, DMX, Swiss Federal Institute of Technology of Lausanne (EPFL), 1015, Lausanne, Switzerland aut Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/2(2000-02-01), 111-116 0957-4530 11:2<111 2000 11 10856 https://doi.org/10.1023/A:1008997118576 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1008997118576 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bohner M. Pharmacy Department, Swiss Federal Institute of Technology of Zurich (ETHZ), Winterthurerstrasse 190, 8057, Zurich, Switzerland aut NATIONALLICENCE 700 1- Merkle H. Pharmacy Department, Swiss Federal Institute of Technology of Zurich (ETHZ), Winterthurerstrasse 190, 8057, Zurich, Switzerland aut NATIONALLICENCE 700 1- Landuyt P. Laboratory of Powder Technology, DMX, Swiss Federal Institute of Technology of Lausanne (EPFL), 1015, Lausanne, Switzerland aut NATIONALLICENCE 700 1- Trophardy G. Laboratory of Powder Technology, DMX, Swiss Federal Institute of Technology of Lausanne (EPFL), 1015, Lausanne, Switzerland aut NATIONALLICENCE 700 1- Lemaitre J. Laboratory of Powder Technology, DMX, Swiss Federal Institute of Technology of Lausanne (EPFL), 1015, Lausanne, Switzerland aut NATIONALLICENCE 773 0- Journal of Materials Science: Materials in Medicine Kluwer Academic Publishers 11/2(2000-02-01), 111-116 0957-4530 11:2<111 2000 11 10856 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer