caa a22 4500 475783700 CHVBK 20180406123652.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1023/A:1008159127672 doi (NATIONALLICENCE)springer-10.1023/A:1008159127672 Olaizola Miguel Aquasearch, Inc., 73-4460 Queen Kaahumanu Hwy., Suite 110, 96740, Kailua-Kona, Hawaii, USA aut Commercial production of astaxanthin from Haematococcus pluvialis using 25,000-liter outdoor photobioreactors [Elektronische Daten] [Miguel Olaizola] Recent developments in photobioreactor technology havemade the production of astaxanthin from Haematococcus pluvialis commercially viable. The coreof our astaxanthin production chain is the AquasearchGrowth Module (AGM), a 25,000 L enclosed andcomputerized outdoor photobioreactor.At Aquasearch's newly expanded facility (dedicatedJanuary 1999), three AGMs (total volume 75,000 L) areused to produce large amounts of clean, fast growing,H. pluvialis. The H. pluvialis biomassproduced in the AGMs is transferred daily to a pondculture system, where carotenogenesis and astaxanthinaccumulation are induced. Following a 5-dayinduction period, the reddened H. pluvialiscells are harvested by gravitational settling. Theharvested biomass, which averages > 2.5 astaxanthinas percent of the dry weight, is transferred to aprocessing building where a high pressure homogenizeris used to rupture the cells' walls. Once the biomasshas been homogenized, it is dried to less than 5%moisture utilizing proprietary drying technology. Thedried product is then ready to be packaged accordingto customer needs.The photobioreactor research program has almostdoubled the performance of the AGMs in the first ninemonths of operations: standing biomass concentrationincreased from 50 to 90 g m-2 and productionincreased from 9 to 13 g m-2 d-1 during thisperiod. Here, we discuss the significance of thesechanges in production parameters to the viability ofcommercial production of astaxanthin and other highvalue products from microalgae. Kluwer Academic Publishers, 2000 astaxanthin nationallicence biomass nationallicence carotenoids nationallicence commercial-scale nationallicence Haematococcus nationallicence nutraceuticals,microalgae nationallicence photobioreactor nationallicence Journal of Applied Phycology Kluwer Academic Publishers 12/3-5(2000-10-01), 499-506 0921-8971 12:3-5<499 2000 12 10811 https://doi.org/10.1023/A:1008159127672 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1008159127672 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Olaizola Miguel Aquasearch, Inc., 73-4460 Queen Kaahumanu Hwy., Suite 110, 96740, Kailua-Kona, Hawaii, USA aut NATIONALLICENCE 773 0- Journal of Applied Phycology Kluwer Academic Publishers 12/3-5(2000-10-01), 499-506 0921-8971 12:3-5<499 2000 12 10811 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer