caa a22 4500 475784200 CHVBK 20180406123653.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s004310051305 doi (NATIONALLICENCE)springer-10.1007/s004310051305 Severe neonatal group A streptococcal disease [Elektronische Daten] [Malgorzata A. Verboon-Maciolek, Tannette G. Krediet, Ingrid van Ertbruggen, Leo J. Gerards, André Fleer] Since the mid-1980s, an increase in incidence of invasive disease caused by group A streptoccoci has been noted amongst adults and children; however, neonatal disease is still rare. Between 1979 and 1998, seven neonates with severe group A streptoccocal disease were admitted to our neonatal intensive care unit. The clinical presentation, treatment and outcome are described. In three cases of early-onset disease vertical transmission was documented. Conclusion Because the incidence of group A streptococcal disease in the general population seems to have increased over the last two decades, we should be aware of the possibility and particularly the severity of group A streptococcal disease in the neonatal period. Springer-Verlag Berlin Heidelberg, 2000 Key words Neonatal infection nationallicence Group A streptococcal disease nationallicence Sepsis nationallicence Meningitis nationallicence Peritonitis nationallicence AbbreviationsGAS group A streptococcal nationallicence TSLS toxic shock-like syndrome nationallicence Verboon-Maciolek Malgorzata A. Department of Neonatology, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85090, 3508 Utrecht, The Netherlands e-mail:m.verboon@wkz.azu.nl Tel.: +31-30-2504545; Fax: +31-30-2505320, NL aut Krediet Tannette G. Department of Neonatology, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85090, 3508 Utrecht, The Netherlands e-mail:m.verboon@wkz.azu.nl Tel.: +31-30-2504545; Fax: +31-30-2505320, NL aut van Ertbruggen Ingrid Department of Neonatology, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85090, 3508 Utrecht, The Netherlands e-mail:m.verboon@wkz.azu.nl Tel.: +31-30-2504545; Fax: +31-30-2505320, NL aut Gerards Leo J. Department of Neonatology, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85090, 3508 Utrecht, The Netherlands e-mail:m.verboon@wkz.azu.nl Tel.: +31-30-2504545; Fax: +31-30-2505320, NL aut Fleer André Department of Medical Microbiology, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85090, 3508 Utrecht, The Netherlands, NL aut https://doi.org/10.1007/s004310051305 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004310051305 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Verboon-Maciolek Malgorzata A. Department of Neonatology, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85090, 3508 Utrecht, The Netherlands e-mail:m.verboon@wkz.azu.nl Tel.: +31-30-2504545; Fax: +31-30-2505320, NL aut NATIONALLICENCE 700 1- Krediet Tannette G. Department of Neonatology, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85090, 3508 Utrecht, The Netherlands e-mail:m.verboon@wkz.azu.nl Tel.: +31-30-2504545; Fax: +31-30-2505320, NL aut NATIONALLICENCE 700 1- van Ertbruggen Ingrid Department of Neonatology, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85090, 3508 Utrecht, The Netherlands e-mail:m.verboon@wkz.azu.nl Tel.: +31-30-2504545; Fax: +31-30-2505320, NL aut NATIONALLICENCE 700 1- Gerards Leo J. Department of Neonatology, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85090, 3508 Utrecht, The Netherlands e-mail:m.verboon@wkz.azu.nl Tel.: +31-30-2504545; Fax: +31-30-2505320, NL aut NATIONALLICENCE 700 1- Fleer André Department of Medical Microbiology, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85090, 3508 Utrecht, The Netherlands, NL aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer