caa a22 4500 475784324 CHVBK 20180406123653.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s004310051308 doi (NATIONALLICENCE)springer-10.1007/s004310051308 Prediction of permanent hearing loss in high-risk preterm infants at term age [Elektronische Daten] [A. Marita Valkama, Kyösti T. Laitakari, E. Uolevi Tolonen, Mirja R.H. Väyrynen, Leena K. Vainionpää, Maila E. Koivisto] The aim of this series was to assess hearing screenings; auditory brainstem responses (ABR), transient evoked otoacoustic emissions (TEOAE) and free field auditory responses (FF) for the prediction of permanent bilateral hearing loss in high-risk preterm infants at term post-conceptional age. A total of 51 preterm infants (gestational age <34 weeks, birth weight <1500 g) underwent examinations at term and hearing, speech and neurological development were followed up until a corrected age of 18 months. Significant hearing defects were verified by broader ABR examinations under sedation and by clinical ward observation including responsiveness to sounds and enhancement of hearing using an amplification device. Seven bilateral fails in ABR were found, together with nine bilateral fails in TEOAE and four fails in FF screening at term age. Six preterm infants were later confirmed to have a significant permanent bilateral hearing loss, four of whom had also cerebral palsy. Bilateral failure in ABR screening predicted hearing loss with a sensitivity of 100% and a specificity of 98%, TEOAE with a sensitivity of 50% and a specificity of 84% and in the FF examination at the levels of 50% and 98%, respectively. Conclusion Transient evoked otoacoustic emissions alone seem not to be so applicable to the neonatal screening of hearing in high-risk preterm infants as shown earlier in full-term infants, possibly because a hearing defect may be due to retrocochlear damage. Consequently, auditory brainstem response screening seems to be more suitable for very low birth weight preterm infants. Springer-Verlag Berlin Heidelberg, 2000 Key words Auditory brainstem responses nationallicence Free field auditory examination nationallicence Hearing loss nationallicence Premature infant nationallicence Transient evoked otoacoustic emission nationallicence AbbreviationsABR auditory brainstem responses nationallicence BOA behavioural observation audiometry nationallicence CP cerebral palsy nationallicence FF free field auditory examination nationallicence GQ general development quotient nationallicence HL hearing level nationallicence SQ sub-quotient nationallicence TEOAE transient evoked otoacoustic emissions nationallicence Valkama A. Marita Department of Paediatrics, University of Oulu, Kajaaninte 52A, 90220 Oulu, Finland e-mail: marita.valkama@oulu.fi Tel.: +358-8-3152011; Fax: +358-8-3155559, FI aut Laitakari Kyösti T. Department of Otorhinolaryngology, University of Oulu, Oulu, Finland, FI aut Tolonen E. Uolevi Department of Clinical Neurophysiology, University of Oulu, Oulu, Finland, FI aut Väyrynen Mirja R.H. Department of Otorhinolaryngology, University of Oulu, Oulu, Finland, FI aut Vainionpää Leena K. Department of Paediatrics, University of Oulu, Kajaaninte 52A, 90220 Oulu, Finland e-mail: marita.valkama@oulu.fi Tel.: +358-8-3152011; Fax: +358-8-3155559, FI aut Koivisto Maila E. Department of Paediatrics, University of Oulu, Kajaaninte 52A, 90220 Oulu, Finland e-mail: marita.valkama@oulu.fi Tel.: +358-8-3152011; Fax: +358-8-3155559, FI aut https://doi.org/10.1007/s004310051308 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004310051308 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Valkama A. Marita Department of Paediatrics, University of Oulu, Kajaaninte 52A, 90220 Oulu, Finland e-mail: marita.valkama@oulu.fi Tel.: +358-8-3152011; Fax: +358-8-3155559, FI aut NATIONALLICENCE 700 1- Laitakari Kyösti T. Department of Otorhinolaryngology, University of Oulu, Oulu, Finland, FI aut NATIONALLICENCE 700 1- Tolonen E. Uolevi Department of Clinical Neurophysiology, University of Oulu, Oulu, Finland, FI aut NATIONALLICENCE 700 1- Väyrynen Mirja R.H. Department of Otorhinolaryngology, University of Oulu, Oulu, Finland, FI aut NATIONALLICENCE 700 1- Vainionpää Leena K. Department of Paediatrics, University of Oulu, Kajaaninte 52A, 90220 Oulu, Finland e-mail: marita.valkama@oulu.fi Tel.: +358-8-3152011; Fax: +358-8-3155559, FI aut NATIONALLICENCE 700 1- Koivisto Maila E. Department of Paediatrics, University of Oulu, Kajaaninte 52A, 90220 Oulu, Finland e-mail: marita.valkama@oulu.fi Tel.: +358-8-3152011; Fax: +358-8-3155559, FI aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer