caa a22 4500 475784626 CHVBK 20180406123654.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s004310051325 doi (NATIONALLICENCE)springer-10.1007/s004310051325 Streptococcus pyogenes meningitis: report of a case and review of the literature [Elektronische Daten] [Reinhard Berner, Silke Herdeg, Nader Gordjani, Matthias Brandis] Streptococcus pyogenes is a very uncommon cause of bacterial meningitis beyond the neonatal period. A case report and a review of the recent literature is presented. We report on a previously healthy 7-year-old boy who developed S. pyogenes meningitis following a 2-day history of otitis media. A CT scan revealed right-sided mastoiditis as a possible focus of infection. The patient was treated with penicillin G for 14 days. The clinical course was uneventful, and he recovered without sequelae. By means of the polymerase chain reaction, the presence of streptococcal pyrogenic exotoxin (SPE) B and SPE C, but not SPE A genes was discovered from the bacterial DNA. Conclusion Streptococcus pyogenes is a rare cause of bacterial meningitis but has to be considered as the causative pathogen beyond the neonatal period. Springer-Verlag Berlin Heidelberg, 2000 Key words Group A Streptococcus nationallicence Streptococcus pyogenes nationallicence Bacterial meningitis nationallicence Otitis media nationallicence Berner Reinhard University Children's Hospital, Mathildenstrasse 1, 79106 Freiburg, Germany e-mail: berner@kkl200.ukl.uni-freiburg.de Tel.: +49-761-2704526 Fax: +49-761-2704481, DE aut Herdeg Silke University Children's Hospital, Mathildenstrasse 1, 79106 Freiburg, Germany e-mail: berner@kkl200.ukl.uni-freiburg.de Tel.: +49-761-2704526 Fax: +49-761-2704481, DE aut Gordjani Nader University Children's Hospital, Mathildenstrasse 1, 79106 Freiburg, Germany e-mail: berner@kkl200.ukl.uni-freiburg.de Tel.: +49-761-2704526 Fax: +49-761-2704481, DE aut Brandis Matthias University Children's Hospital, Mathildenstrasse 1, 79106 Freiburg, Germany e-mail: berner@kkl200.ukl.uni-freiburg.de Tel.: +49-761-2704526 Fax: +49-761-2704481, DE aut https://doi.org/10.1007/s004310051325 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004310051325 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Berner Reinhard University Children's Hospital, Mathildenstrasse 1, 79106 Freiburg, Germany e-mail: berner@kkl200.ukl.uni-freiburg.de Tel.: +49-761-2704526 Fax: +49-761-2704481, DE aut NATIONALLICENCE 700 1- Herdeg Silke University Children's Hospital, Mathildenstrasse 1, 79106 Freiburg, Germany e-mail: berner@kkl200.ukl.uni-freiburg.de Tel.: +49-761-2704526 Fax: +49-761-2704481, DE aut NATIONALLICENCE 700 1- Gordjani Nader University Children's Hospital, Mathildenstrasse 1, 79106 Freiburg, Germany e-mail: berner@kkl200.ukl.uni-freiburg.de Tel.: +49-761-2704526 Fax: +49-761-2704481, DE aut NATIONALLICENCE 700 1- Brandis Matthias University Children's Hospital, Mathildenstrasse 1, 79106 Freiburg, Germany e-mail: berner@kkl200.ukl.uni-freiburg.de Tel.: +49-761-2704526 Fax: +49-761-2704481, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer