caa a22 4500 475784685 CHVBK 20180406123654.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s004310051326 doi (NATIONALLICENCE)springer-10.1007/s004310051326 Schistosomiasis in German children [Elektronische Daten] [Ralf Bialek, Jürgen Knobloch] Reports on schistosomiasis in children growing up in Europe are rare despite increased travel activity. We report on eight male and three female German children aged 50 months to 15 years with schistosomiasis. Six children were asymptomatic, whereas two presented with typical signs of Katayama fever. Persisting haematuria, headache with eosinophilia and pyelonephritis were observed in one child each. An exposure was reported for six of the children. Two were examined solely because schistosomiasis was diagnosed in a family member. All had antibodies against schistosomal antigens in at least two of three screening tests. However, schistosomal ova (Schistosoma haematobium) were detected in urine and faecal specimens from only three children. A tumour-like lesion of the bladder was found by ultrasound in only one of the children who also exhibited haematuria. Neither eosinophilia nor elevated IgE levels were constant findings. Six to 12 months after praziquantel treatment, parasitological and ultrasound checks were negative and levels of specific antibodies decreased. However, 2 years later, elevated antibody levels were detected in one girl without evidence of any new exposure. She became antibody-negative 1 year after a second course of treatment. Conclusion In contrast to residents of endemic areas, parasitological and ultrasound examinations seem to be inferior to immunodiagnostics in children from non-endemic areas at temporary risk for schistosomiasis. Springer-Verlag Berlin Heidelberg, 2000 Key words Schistosomiasis nationallicence Children nationallicence Travellers nationallicence Ultrasonography nationallicence Immunodiagnosis nationallicence Bialek Ralf Institut für Tropenmedizin, Universitätsklinikum Tübingen, Keplerstrasse 15, 72074 Tübingen, Germany e-mail: ralf.bialek@med.uni-tuebingen.de Tel.: +49-7071-2982367 Fax: +49-7071-295267, DE aut Knobloch Jürgen Institut für Tropenmedizin, Universitätsklinikum Tübingen, Keplerstrasse 15, 72074 Tübingen, Germany e-mail: ralf.bialek@med.uni-tuebingen.de Tel.: +49-7071-2982367 Fax: +49-7071-295267, DE aut https://doi.org/10.1007/s004310051326 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004310051326 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bialek Ralf Institut für Tropenmedizin, Universitätsklinikum Tübingen, Keplerstrasse 15, 72074 Tübingen, Germany e-mail: ralf.bialek@med.uni-tuebingen.de Tel.: +49-7071-2982367 Fax: +49-7071-295267, DE aut NATIONALLICENCE 700 1- Knobloch Jürgen Institut für Tropenmedizin, Universitätsklinikum Tübingen, Keplerstrasse 15, 72074 Tübingen, Germany e-mail: ralf.bialek@med.uni-tuebingen.de Tel.: +49-7071-2982367 Fax: +49-7071-295267, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer