caa a22 4500 475785339 CHVBK 20180406123656.0 cr unu---uuuuu 170329e20000201xx s 000 0 eng 10.1007/s004310050042 doi (NATIONALLICENCE)springer-10.1007/s004310050042 Acute respiratory distress syndrome in children with acute iron poisoning: the role of intravenous desferrioxamine [Elektronische Daten] [A. S. Ioannides, J. M. Panisello] The acute respiratory distress syndrome is a rare but potentially fatal complication of severe acute iron poisoning and its pathogenesis has been linked with direct and indirect iron toxicity as well as the use of the chelator drug desferrioxamine. We report a case of severe acute respiratory decompensation in a child treated according to the current protocol for chelation therapy and discuss its implications. Conclusion We believe that the efficacy and safety of chelation therapy in severe acute iron poisoning may be improved by targeting the initial high levels of readily chelatable serum iron with adequate doses of desferrioxamine without prolonging its use unnecessarily. Springer-Verlag Berlin Heidelberg, 2000 Key words Acute respiratory distress syndrome nationallicence Acute iron poisoning nationallicence Desferrioxamine nationallicence Ioannides A. S. Department of Paediatric Intensive Care, Royal Manchester Children's Hospital, Hospital Road, Pendlebury, Manchester M27 4HA, UK e-mail: aioannides@aioannides.ndirect.co.uk Tel.: +44-161-727-2468; Fax: +44-161-727-2198, GB aut Panisello J. M. Department of Paediatric Intensive Care, Royal Manchester Children's Hospital, Hospital Road, Pendlebury, Manchester M27 4HA, UK e-mail: aioannides@aioannides.ndirect.co.uk Tel.: +44-161-727-2468; Fax: +44-161-727-2198, GB aut https://doi.org/10.1007/s004310050042 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004310050042 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ioannides A. S. Department of Paediatric Intensive Care, Royal Manchester Children's Hospital, Hospital Road, Pendlebury, Manchester M27 4HA, UK e-mail: aioannides@aioannides.ndirect.co.uk Tel.: +44-161-727-2468; Fax: +44-161-727-2198, GB aut NATIONALLICENCE 700 1- Panisello J. M. Department of Paediatric Intensive Care, Royal Manchester Children's Hospital, Hospital Road, Pendlebury, Manchester M27 4HA, UK e-mail: aioannides@aioannides.ndirect.co.uk Tel.: +44-161-727-2468; Fax: +44-161-727-2198, GB aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer