caa a22 4500 475786017 CHVBK 20180406123658.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/s004310050072 doi (NATIONALLICENCE)springer-10.1007/s004310050072 Effect on lung function of continuous positive airway pressure administered either by infant flow driver or a single nasal prong [Elektronische Daten] [Vasiliki Kavvadia, Anne Greenough, Gabriel Dimitriou] The aim of this study was to assess if continuous positive airways pressure (CPAP) delivered by an infant flow driver (IFD) was a more effective method of improving lung function than delivering CPAP by a single nasal prong. A total of 36 infants (median gestational age 29 weeks, range 25-35 weeks) were studied, 12 who received CPAP via an IFD, 12 who received CPAP via a single nasal prong and 12 without CPAP. CPAP was administered post extubation if apnoeas and bradycardias or a respiratory acidosis developed or electively if the infant was of birth weight <1.0 kg. Lung function was assessed by the supplementary oxygen requirement and measurement of compliance of the respiratory system using an occlusion technique. Assessments were made immediately prior to and after 24 h of CPAP administration and at similar postnatal ages in the non-CPAP group. The infants who did not require CPAP had better lung function (non significant) than the other two groups before they received CPAP. After 24 h, lung function had improved in both CPAP groups to the level of the non CPAP infants. The supplementary oxygen requirements of all three groups decreased over the 24 h period, but this only reached significance in the single nasal prong group (P < 0.05). Four infants supported by the IFD, but none with a single nasal prong, became hyperoxic. Conclusion Continuous positive airways pressure administration via the infant flow driver appears to offer no short-term advantage over a single nasal prong system when used after extubation in preterm infants. Springer-Verlag Berlin Heidelberg, 2000 Key words Continuous positive airways pressure nationallicence Infant flow driver nationallicence Lung function nationallicence Kavvadia Vasiliki Children Nationwide Regional Neonatal Intensive Care Centre, King's College Hospital, London, UK e-mail: anne.greenough@kcl.ac.uk Tel.: +44-171-346-3037; Fax: +44-171-924-9365, GB aut Greenough Anne Children Nationwide Regional Neonatal Intensive Care Centre, King's College Hospital, London, UK e-mail: anne.greenough@kcl.ac.uk Tel.: +44-171-346-3037; Fax: +44-171-924-9365, GB aut Dimitriou Gabriel Children Nationwide Regional Neonatal Intensive Care Centre, King's College Hospital, London, UK e-mail: anne.greenough@kcl.ac.uk Tel.: +44-171-346-3037; Fax: +44-171-924-9365, GB aut https://doi.org/10.1007/s004310050072 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004310050072 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kavvadia Vasiliki Children Nationwide Regional Neonatal Intensive Care Centre, King's College Hospital, London, UK e-mail: anne.greenough@kcl.ac.uk Tel.: +44-171-346-3037; Fax: +44-171-924-9365, GB aut NATIONALLICENCE 700 1- Greenough Anne Children Nationwide Regional Neonatal Intensive Care Centre, King's College Hospital, London, UK e-mail: anne.greenough@kcl.ac.uk Tel.: +44-171-346-3037; Fax: +44-171-924-9365, GB aut NATIONALLICENCE 700 1- Dimitriou Gabriel Children Nationwide Regional Neonatal Intensive Care Centre, King's College Hospital, London, UK e-mail: anne.greenough@kcl.ac.uk Tel.: +44-171-346-3037; Fax: +44-171-924-9365, GB aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer