caa a22 4500 475786114 CHVBK 20180406123658.0 cr unu---uuuuu 170329e20000101xx s 000 0 eng 10.1007/s004310050003 doi (NATIONALLICENCE)springer-10.1007/s004310050003 Persistent acquired lobar overinflation complicating bronchopulmonary dysplasia [Elektronische Daten] [C. Murray, D. W. Pilling, N. J. Shaw] Persistent acquired lobar overinflation (PALO) may complicate bronchopulmonary dysplasia (BPD). From infants admitted to the regional neonatal intensive care unit or who had been followed up at the chronic lung disease clinic in Liverpool over a 6.5-year period, 11 children with BPD and PALO were identified and details of their neonatal and subsequent outcome obtained. Their median gestational age was 29 weeks (range 24-33) and median birth weight was 1317 g (range 676-1968 g). All had received ventilatory support for severe neonatal respiratory distress syndrome for a median of 26 days (range 5-86). The median age the acquired lobar overinflation was detected was 82 days (range 45-424 days). Nine patients required continued neonatal or paediatric intensive care re-admission for deteriorating respiratory function. Six children have subsequently died at a median age of 9.5 months (range 6.5-20). Five patients underwent bronchoscopy, four suggesting the presence of bronchomalacia. Three patients had ventilation-perfusion scans all showing that the overinflated lobe had no mismatch defect unlike other areas of the lung. Conclusion The place of specific therapies for persistent acquired lobar overinflation is unclear. Surgery to remove the overinflated lobe in such cases may be inappropriate and the outcome of this complication of bronchopulmonary dysplasia appears to be poor. Springer-Verlag Berlin Heidelberg, 2000 Key words Bronchopulmonary dysplasia nationallicence Lobar overinflation nationallicence Murray C. Neonatal Unit, Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS, UK, e-mail: njbshaw@yahoo.com, Tel.: +44-151-708 9988, GB aut Pilling D. W. Neonatal Unit, Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS, UK, e-mail: njbshaw@yahoo.com, Tel.: +44-151-708 9988, GB aut Shaw N. J. Neonatal Unit, Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS, UK, e-mail: njbshaw@yahoo.com, Tel.: +44-151-708 9988, GB aut https://doi.org/10.1007/s004310050003 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004310050003 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Murray C. Neonatal Unit, Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS, UK, e-mail: njbshaw@yahoo.com, Tel.: +44-151-708 9988, GB aut NATIONALLICENCE 700 1- Pilling D. W. Neonatal Unit, Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS, UK, e-mail: njbshaw@yahoo.com, Tel.: +44-151-708 9988, GB aut NATIONALLICENCE 700 1- Shaw N. J. Neonatal Unit, Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS, UK, e-mail: njbshaw@yahoo.com, Tel.: +44-151-708 9988, GB aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer