caa a22 4500 475786130 CHVBK 20180406123658.0 cr unu---uuuuu 170329e20000101xx s 000 0 eng 10.1007/s004310050023 doi (NATIONALLICENCE)springer-10.1007/s004310050023 Sclerosing cholangitis associated to cryptosporidiosis in liver-transplanted children [Elektronische Daten] [M. Campos, E. Jouzdani, C. Sempoux, J. P. Buts, R. Reding, J. B. Otte, E. M. Sokal] Three children of a series of 461 pediatric liver transplant recipients developed diffuse cholangitis associated with intestinal cryptosporidium carriage. All three received immunosuppression consisting of tacrolimus and prednisone. Cryprosporidium carriage was treated with paramomycin, while immunosuppression was decreased according to graft tolerance. No other infectious pathogens were found, and no vascular problems were detected. Bile duct anastomosis was reoperated in all three, but biliary cirrhosis developed in one patient, requiring retransplantation. All three patients are alive and well, and free of intestinal parasites on follow-up. Conclusion Cryptosporidium intestinal infection may play a role in some cases of otherwise unexplained cholangiopathies in pediatric liver transplant recipients. This may lead to significant morbidity, including need for retransplantation. Springer-Verlag Berlin Heidelberg, 2000 Key words Cryptosporidium nationallicence Cholangitis nationallicence Transplant nationallicence Campos M. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut Jouzdani E. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut Sempoux C. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut Buts J. P. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut Reding R. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut Otte J. B. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut Sokal E. M. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut https://doi.org/10.1007/s004310050023 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004310050023 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Campos M. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut NATIONALLICENCE 700 1- Jouzdani E. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut NATIONALLICENCE 700 1- Sempoux C. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut NATIONALLICENCE 700 1- Buts J. P. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut NATIONALLICENCE 700 1- Reding R. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut NATIONALLICENCE 700 1- Otte J. B. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut NATIONALLICENCE 700 1- Sokal E. M. University of Louvain, Cliniques St. Luc, Departement de Pédiatrie, 10/1301 Av. Hippocrate, 1200 Brussels, Belgium e-mail: Sokal@pedi.ucl.ac.be Tel.: +32-2-7641386; Fax: +32-2-7648909, BE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer