caa a22 4500 475786548 CHVBK 20180406123659.0 cr unu---uuuuu 170329e20000701xx s 000 0 eng 10.1007/s004310000447 doi (NATIONALLICENCE)springer-10.1007/s004310000447 Longitudinal growth in HIV-negative boys with haemophilia [Elektronische Daten] [Jan Lebl, Jutta Falger, Thomas Zidek, Christoph Male, Vladimir Komrska, Herwig Frisch] It has been shown that HIV-positive haemophilic children develop growth retardation. As not only the HIV infection but also other disease-related factors might compromise growth in these children, growth data were analysed in a longitudinal cross-sectional manner in 84 HIV-negative haemophilic patients from two university clinics. A total of 2-24 height and weight measurements (median 6) were recorded in each patient resulting in 683 single values collected between 1977-1995. Height SDS of all haemophilic boys was −0.31 ± 2.13 (mean ± SD, NS versus 0) and body mass index SDS was 0.21 ± 3.49 (mean SD, NS versus 0) at first measurement and remained unchanged throughout the observation period. Neither height nor body mass index differed with respect to the severity of haemophilia (mild/moderate/severe) or the study centre (Vienna/Prague). Conclusion Growth in HIV-negative patients with haemophilia is not affected in spite of the immunological abnormalities attributed to the substitution therapy or the bleeding episodes in the joints with the potential effect on the growth plate. Springer-Verlag Berlin Heidelberg, 2000 Key words Haemophilia nationallicence HIV-negative patients nationallicence Children nationallicence Growth nationallicence Body mass index nationallicence Lebl Jan Department of Paediatrics, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic aut Falger Jutta Department of Paediatrics, University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria, AT aut Zidek Thomas Department of Epidemiology, Institute of Tumour Biology and Cancer Research, University of Vienna, Vienna, Austria, AT aut Male Christoph Department of Paediatrics, University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria, AT aut Komrska Vladimir 2nd Department of Paediatrics, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic aut Frisch Herwig Department of Paediatrics, University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria, AT aut https://doi.org/10.1007/s004310000447 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004310000447 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lebl Jan Department of Paediatrics, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic aut NATIONALLICENCE 700 1- Falger Jutta Department of Paediatrics, University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria, AT aut NATIONALLICENCE 700 1- Zidek Thomas Department of Epidemiology, Institute of Tumour Biology and Cancer Research, University of Vienna, Vienna, Austria, AT aut NATIONALLICENCE 700 1- Male Christoph Department of Paediatrics, University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria, AT aut NATIONALLICENCE 700 1- Komrska Vladimir 2nd Department of Paediatrics, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic aut NATIONALLICENCE 700 1- Frisch Herwig Department of Paediatrics, University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria, AT aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer