caa a22 4500 475787439 CHVBK 20180406123703.0 cr unu---uuuuu 170329e20001201xx s 000 0 eng 10.1007/s004140000132 doi (NATIONALLICENCE)springer-10.1007/s004140000132 Population genetics of the hypervariable locus D12S391 in Koreans [Elektronische Daten] [Y.-W. Lee, I.-H. Kang, S.-M. Kim, H.-L. Lee, T.-W. Koo, H.-S. Lee, J.-J. Hwang] The hypervariable short tandem repeat (STR) locus D12S391 was investigated in a Korean population and 34 fragments were sequenced to confirm the structure of alleles. From these sequenced fragments an allelic ladder containing 13 sequenced alleles was constructed. From 595 unrelated Koreans, 14 alleles were detected and one variant allele 19.3 was observed. The observed heterozygosity was 0.795 and no deviation from Hardy-Weinberg equilibrium was observed in the Korean population (p = 0.606). The allele frequency distribution in the Korean population was not similar to other racial or ethnic groups except for Egyptians, Yemenis, Japanese and Caucasoids from the Rhine area. No mutations were observed in the 702 meioses from 144 Korean families. This study demonstrates that the STR locus D12S391 is a useful tool for forensic identification and parentage testing. Springer-Verlag Berlin Heidelberg, 2000 Key words Short tandem repeat nationallicence D12S391 nationallicence Allele nationallicence frequency nationallicence Population study nationallicence Korean population nationallicence Lee Y.-W Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut Kang I.-H Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut Kim S.-M Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut Lee H.-L Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut Koo T.-W Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut Lee H.-S Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut Hwang J.-J Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut https://doi.org/10.1007/s004140000132 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004140000132 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lee Y.-W Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut NATIONALLICENCE 700 1- Kang I.-H Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut NATIONALLICENCE 700 1- Kim S.-M Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut NATIONALLICENCE 700 1- Lee H.-L Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut NATIONALLICENCE 700 1- Koo T.-W Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut NATIONALLICENCE 700 1- Lee H.-S Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut NATIONALLICENCE 700 1- Hwang J.-J Department of Legal Medicine, College of Medicine, Korea University, 126-1 5Ga, Anam-Dong, Sungbuk-Ku, Seoul 136-705, Korea e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9283901; Fax: +82-2-9206148, KR aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer