caa a22 4500 475787528 CHVBK 20180406123703.0 cr unu---uuuuu 170329e20001201xx s 000 0 eng 10.1007/s004140000153 doi (NATIONALLICENCE)springer-10.1007/s004140000153 Highly informative Y-chromosomal haplotypes by the addition of three new STRs DYS437, DYS438 and DYS439 [Elektronische Daten] [P. Grignani, G. Peloso, P. Fattorini, C. Previderè] The Y chromosome STRs DYS437, DYS438 and DYS439 were selected from publicly available genome databases and used to analyse an Italian population sample. A tetraplex PCR reaction including the highly informative DYS385 locus, was set up and used for the analysis of 131 male samples to determine allele frequencies and STR diversity values. The number of different haplotypes and the haplotype diversity value found from the analysis of the STRs included in the tetraplex reaction were very similar to those found from the analysis of the basic set of 7 Y-STRs (DYS19, DYS389I/II, DYS390, DYS391, DYS392 and DYS393) previously carried out on the same population sample. By combining the allelic states of the 11 Y-chromosomal STRs we could construct highly informative haplotypes that allowed the discrimination of 93.8% (120 out of 128) of the samples tested. This approach represents a very powerful tool for individual identification and paternity testing in forensic medicine. Springer-Verlag Berlin Heidelberg, 2000 Key words Y-chromosome nationallicence STRs nationallicence Y-haplotypes nationallicence Grignani P. IRCCS Policlinico S. Matteo, Pavia, Servizio di Medicina Legale, Dipartimento di Medicina Legale e Sanità Pubblica, via Forlanini 12, 27100, Pavia, Italy, IT aut Peloso G. Dipartimento di Medicina Legale e Sanità Pubblica, via Forlanini 12, 27100 Pavia, Italy e-mail: previde@unipv.it, Fax: +39-0382-528025, IT aut Fattorini P. Istituto di Medicina Legale, via Molino a Vento 123, 34147 Trieste, Italy, IT aut Previderè C. Dipartimento di Medicina Legale e Sanità Pubblica, via Forlanini 12, 27100 Pavia, Italy e-mail: previde@unipv.it, Fax: +39-0382-528025, IT aut https://doi.org/10.1007/s004140000153 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004140000153 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Grignani P. IRCCS Policlinico S. Matteo, Pavia, Servizio di Medicina Legale, Dipartimento di Medicina Legale e Sanità Pubblica, via Forlanini 12, 27100, Pavia, Italy, IT aut NATIONALLICENCE 700 1- Peloso G. Dipartimento di Medicina Legale e Sanità Pubblica, via Forlanini 12, 27100 Pavia, Italy e-mail: previde@unipv.it, Fax: +39-0382-528025, IT aut NATIONALLICENCE 700 1- Fattorini P. Istituto di Medicina Legale, via Molino a Vento 123, 34147 Trieste, Italy, IT aut NATIONALLICENCE 700 1- Previderè C. Dipartimento di Medicina Legale e Sanità Pubblica, via Forlanini 12, 27100 Pavia, Italy e-mail: previde@unipv.it, Fax: +39-0382-528025, IT aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer