caa a22 4500 475787625 CHVBK 20180406123703.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s004149900103 doi (NATIONALLICENCE)springer-10.1007/s004149900103 Thickness of the air-blood tissue barrier in infants [Elektronische Daten] [T. Bajanowski, B. Brinkmann] The harmonic mean barrier thickness of the alveolar air-blood tissue barrier was measured in nine SIDS cases, six cases of unnatural death (three with asphyxiation, three without asphyxiation) and six cases showing interstitial pneumonia (IP, three cases with lymphomonocyte infiltration of alveolar walls, three cases with peribronchiolar infiltration). Approximately 550-600 measurements were carried out in each case using micrographs with a final magnification of 11,000. The T h values ranged between 0.37 μm and 0.39 μm in the SIDS group, in deaths due to asphyxiation and IP with a peribronchiolar type of infiltration, were lowest in the unnatural deaths without asphyxiation (0.32 μm) and highest in cases showing IP with alveoloseptal infiltration (0.44 μm). The differences between the groups were significant (H-test, ¶Hcor = 5.927). Compared to "normal” unnatural deaths ¶(T h = 0.32 μm), cases with interstitial cell infiltration of the alveolar septa showed a nearly 40% increase of the barrier thickness which indicates a corresponding decrease of the diffusion capacity. A decreased diffusion capacity can cause hypoxemia which could be an additional trigger mechanism in the death process. Springer-Verlag Berlin Heidelberg, 2000 Key words Sudden infant death (SID) nationallicence Interstitial pneumonia nationallicence Pulmonary diffusion capacity nationallicence Alveolar ¶air-blood barrier nationallicence Hypoxia nationallicence Bajanowski T. Institute of Legal Medicine, Von Esmarch-Strasse 62, 48149 Münster, Germany e-mail: brinkma@uni-muenster.de; Tel.: +49-251-8355161; Fax: +49-251-8355158, DE aut Brinkmann B. Institute of Legal Medicine, Von Esmarch-Strasse 62, 48149 Münster, Germany e-mail: brinkma@uni-muenster.de; Tel.: +49-251-8355161; Fax: +49-251-8355158, DE aut https://doi.org/10.1007/s004149900103 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004149900103 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bajanowski T. Institute of Legal Medicine, Von Esmarch-Strasse 62, 48149 Münster, Germany e-mail: brinkma@uni-muenster.de; Tel.: +49-251-8355161; Fax: +49-251-8355158, DE aut NATIONALLICENCE 700 1- Brinkmann B. Institute of Legal Medicine, Von Esmarch-Strasse 62, 48149 Münster, Germany e-mail: brinkma@uni-muenster.de; Tel.: +49-251-8355161; Fax: +49-251-8355158, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer