caa a22 4500 475787927 CHVBK 20180406123704.0 cr unu---uuuuu 170329e20000801xx s 000 0 eng 10.1007/s004149900112 doi (NATIONALLICENCE)springer-10.1007/s004149900112 Analysis of eight STR loci in two Hungarian populations [Elektronische Daten] [B. Egyed, S. Füredi, M. Angyal, L. Boutrand, A. Vandenberghe, J. Woller, Z. Pádár] A multiplex reaction for the eight STR loci D3S1358, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820 was used to generate allele frequency databases for two Hungarian population samples, Caucasians from the Budapest area and Romanies from Baranya county. During the analysis two intermediate-sized alleles and a sequence variant allele were observed at the D7S820 locus. All three types of allelic variants were found to have modifications in the same block of a (T)9 stretch located within the 3′ flanking region of each allele, which may indicate a possible higher mutation rate of this (T)9 block. For the loci D3S1358 and D7S820 the Romany population database showed departures from Hardy-Weinberg equilibrium. The forensic efficiency values for the Romany population were slightly different from those found in the Hungarian Caucasian population. Comparing the allele frequency values by G-statistic, calculating the FST indices and with the pair-wise comparisons of inter-population variance, the two Hungarian populations could be distinguished using data from the eight STR loci. Springer-Verlag Berlin Heidelberg, 2000 Key words Multiplex STR profiling nationallicence Capillary ¶electrophoresis nationallicence Variant alleles nationallicence Romany population nationallicence Population genetics nationallicence Egyed B. Department of Biology, Institute for Forensic Sciences, P.O. Box 314/4, 1903 Budapest, Hungary, HU aut Füredi S. Department of Biology, Institute for Forensic Sciences, P.O. Box 314/4, 1903 Budapest, Hungary, HU aut Angyal M. Department of Forensic Medicine, Medical University School of Pécs, P.O. Box 99, 7643 Pécs, Hungary, HU aut Boutrand L. Laboratory of Human Molecular Genetics, Faculty of Pharmacy, University Claude Bernard Lyon 1, 69008 Lyon, France, FR aut Vandenberghe A. Laboratory of Human Molecular Genetics, Faculty of Pharmacy, University Claude Bernard Lyon 1, 69008 Lyon, France, FR aut Woller J. Department of Biology, Institute for Forensic Sciences, P.O. Box 314/4, 1903 Budapest, Hungary, HU aut Pádár Z. Department of Biology, Institute for Forensic Sciences, P.O. Box 314/4, 1903 Budapest, Hungary, HU aut https://doi.org/10.1007/s004149900112 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004149900112 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Egyed B. Department of Biology, Institute for Forensic Sciences, P.O. Box 314/4, 1903 Budapest, Hungary, HU aut NATIONALLICENCE 700 1- Füredi S. Department of Biology, Institute for Forensic Sciences, P.O. Box 314/4, 1903 Budapest, Hungary, HU aut NATIONALLICENCE 700 1- Angyal M. Department of Forensic Medicine, Medical University School of Pécs, P.O. Box 99, 7643 Pécs, Hungary, HU aut NATIONALLICENCE 700 1- Boutrand L. Laboratory of Human Molecular Genetics, Faculty of Pharmacy, University Claude Bernard Lyon 1, 69008 Lyon, France, FR aut NATIONALLICENCE 700 1- Vandenberghe A. Laboratory of Human Molecular Genetics, Faculty of Pharmacy, University Claude Bernard Lyon 1, 69008 Lyon, France, FR aut NATIONALLICENCE 700 1- Woller J. Department of Biology, Institute for Forensic Sciences, P.O. Box 314/4, 1903 Budapest, Hungary, HU aut NATIONALLICENCE 700 1- Pádár Z. Department of Biology, Institute for Forensic Sciences, P.O. Box 314/4, 1903 Budapest, Hungary, HU aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer