caa a22 4500 475790782 CHVBK 20180406123710.0 cr unu---uuuuu 170329e20000401xx s 000 0 eng 10.1007/s004230050261 doi (NATIONALLICENCE)springer-10.1007/s004230050261 Hepatoma of the liver - resection or transplantation? [Elektronische Daten] [P. Neuhaus, S. Jonas, W. O. Bechstein] Abstract : Introduction: Despite recent advances with techniques of in situ tumor ablation, surgical therapy remains at present the mainstay in the treatment of primary hepatic malignancies. Discussion: After an initial endeavor to establish liver transplantation as a treatment option, especially for unresectable liver tumors, only a few indications, for example early hepatocellular carcinoma in cirrhosis, are currently agreed upon. Other indications, such as peripheral cholangiocarcinoma and hepatocellular carcinoma in non-cirrhotics, have largely been abandoned or are still under debate, as with fibrolamellar carcinoma. Selection of patients suffering from hepatocellular carcinoma in cirrhosis for liver transplantation is still based on tumor size and node number, because the current state of diagnostic imaging fails to reliably predict the most important prognostic parameter: vascular infiltration. Other selection criteria are under investigation. Studies on multimodal therapy are also underway but have not yet demonstrated a benefit. Springer-Verlag Berlin Heidelberg, 2000 Key words Hepatoma nationallicence Liver resection nationallicence Liver transplantation nationallicence Neuhaus P. Department of Visceral and Transplantation Surgery, Charité, Campus Virchow Clinic, Augustenburger Platz 1, D-13353 Berlin, Germany Tel: +49-30-45052001 Fax: +49-30-45052900, DE aut Jonas S. Department of Visceral and Transplantation Surgery, Charité, Campus Virchow Clinic, Augustenburger Platz 1, D-13353 Berlin, Germany Tel: +49-30-45052001 Fax: +49-30-45052900, DE aut Bechstein W. O. Department of Visceral and Transplantation Surgery, Charité, Campus Virchow Clinic, Augustenburger Platz 1, D-13353 Berlin, Germany Tel: +49-30-45052001 Fax: +49-30-45052900, DE aut https://doi.org/10.1007/s004230050261 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004230050261 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Neuhaus P. Department of Visceral and Transplantation Surgery, Charité, Campus Virchow Clinic, Augustenburger Platz 1, D-13353 Berlin, Germany Tel: +49-30-45052001 Fax: +49-30-45052900, DE aut NATIONALLICENCE 700 1- Jonas S. Department of Visceral and Transplantation Surgery, Charité, Campus Virchow Clinic, Augustenburger Platz 1, D-13353 Berlin, Germany Tel: +49-30-45052001 Fax: +49-30-45052900, DE aut NATIONALLICENCE 700 1- Bechstein W. O. Department of Visceral and Transplantation Surgery, Charité, Campus Virchow Clinic, Augustenburger Platz 1, D-13353 Berlin, Germany Tel: +49-30-45052001 Fax: +49-30-45052900, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer