caa a22 4500 475790847 CHVBK 20180406123710.0 cr unu---uuuuu 170329e20000401xx s 000 0 eng 10.1007/s004230050264 doi (NATIONALLICENCE)springer-10.1007/s004230050264 Surgical management of gastrointestinal stromal tumors of the stomach [Elektronische Daten] [M. Knoop, K. St. Friedrichs, J. Dierschke] Abstract : Background: Gastrointestinal stromal tumors (GISTs) are rare tumors of the GI tract with varying degree of dignity and prognosis. Intramural or extragastral growth of gastric GISTs is associated with diagnostic difficulties and uncertainty about the type and extent of surgical therapy. Based on our experience, we tried to formulate management guidelines for gastric GISTs. Methods: Five patients with gastric GIST (36-85 years old) underwent subserosal excision with subsequent B-II resection (1×), full-thickness partial gastric resection (2×), gastrotomy with submucosal excision (1×), or gastrectomy for carcinoma with an incidental finding of a leiomyoma (1×). Results: Tumor size ranged from 2×2×1 cm to 9×6×4 cm. These tumors were classified as epithelioid leiomyosarcoma (1×), GIST (3×), or leiomyoma (1×). The prognosis of risk ranged from no risk (leiomyoma) to low-malignancy (leiomyosarcoma) depending on tumor size and mitotic index. No recurrent disease has been noted so far during follow-up ranging from 3 months to 6 years. Conclusions: Staging of gastric disease should include the probability of gastric GIST. Surgical resection is the therapy of choice for potential malignant GISTs to ensure a local radical removal. Metachronic metastases should be resected if possible. Depending on tumor stage and prognostic parameters, an individual follow-up with endoscopic and radiologic examinations is recommended. Further studies should be undertaken to elaborate prognostic determinants and stage-adapted treatment. Springer-Verlag Berlin Heidelberg, 2000 Key words Gastrointestinal stromal tumor nationallicence Stomach nationallicence Gastric resection nationallicence Knoop M. Department of General and Visceral Surgery, Johanniter Hospital, Stendal, Germany, DE aut Friedrichs K. St Department of General and Visceral Surgery, Johanniter Hospital, Stendal, Germany, DE aut Dierschke J. Department of General and Visceral Surgery, Johanniter Hospital, Stendal, Germany, DE aut https://doi.org/10.1007/s004230050264 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004230050264 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Knoop M. Department of General and Visceral Surgery, Johanniter Hospital, Stendal, Germany, DE aut NATIONALLICENCE 700 1- Friedrichs K. St Department of General and Visceral Surgery, Johanniter Hospital, Stendal, Germany, DE aut NATIONALLICENCE 700 1- Dierschke J. Department of General and Visceral Surgery, Johanniter Hospital, Stendal, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer