caa a22 4500 475791312 CHVBK 20180406123711.0 cr unu---uuuuu 170329e20000201xx s 000 0 eng 10.1023/A:1006349123217 doi (NATIONALLICENCE)springer-10.1023/A:1006349123217 Computerized left ventricular pressure-volume relationships (pV-loops) using disposable angiographic tip transducer pigtail catheters [Elektronische Daten] [Ulrich Raff, Talley Culclasure, Cathy Clark, Lana Overturf, Bertron Groves] Left ventricular pressure-volume relationships expressed as pV loops could yield important hemodynamic information in the cardiac catheterization laboratory. Many clinical situations might benefit from a quantitative assessment of left ventricular function. Potential applications of pV loops include the assessment of vasoactive and inotropic drugs, balloon valvuloplasty, coronary angioplasty, and surgical treatment of valvular heart disease. For many years the clinical use of pV loops has been hindered by logistical difficulties. The ability to merge on-line concurrent digital imaging data for computation of left ventricular volume and digital left ventricular pressure wave forms obtained from high fidelity tip-transducer angiocatheters has allowed us to develop a technique which can generate pV loops during cardiac catheterization procedures. The method offers an automated measurement of left ventricular volume independent of edge detection or an interactive technique for tracing endocardial borders by a trained operator. Illustrative case studies are included to demonstrate the potential of the method during ventricular angiographic procedures. Implementation and computational time requirements of the method are discussed. The concept and the value of pV loop generation to study left ventricular performance has been known for many years. Combining digital imaging and digital physiologic data obtained with disposable tip-transducer angiocatheters with modern networking technology, the technique can more easily be applied to catheterization procedures and could enhance invasive hemodynamic assessment of left ventricular function. Kluwer Academic Publishers, 2000 left ventricular angiogram nationallicence Millar pigtail catheter nationallicence myocardial compliance nationallicence pressure-volume relationship nationallicence Raff Ulrich Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO aut Culclasure Talley Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO aut Clark Cathy Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO aut Overturf Lana Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO aut Groves Bertron Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO aut The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/1(2000-02-01), 13-21 0167-9899 16:1<13 2000 16 10554 https://doi.org/10.1023/A:1006349123217 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1006349123217 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Raff Ulrich Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO aut NATIONALLICENCE 700 1- Culclasure Talley Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO aut NATIONALLICENCE 700 1- Clark Cathy Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO aut NATIONALLICENCE 700 1- Overturf Lana Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO aut NATIONALLICENCE 700 1- Groves Bertron Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO aut NATIONALLICENCE 773 0- The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/1(2000-02-01), 13-21 0167-9899 16:1<13 2000 16 10554 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer