caa a22 4500 475791479 CHVBK 20180406123712.0 cr unu---uuuuu 170329e20001201xx s 000 0 eng 10.1023/A:1010643426720 doi (NATIONALLICENCE)springer-10.1023/A:1010643426720 3D coronary reconstruction from routine single-plane coronary angiograms: Clinical validation and quantitative analysis of the right coronary artery in 100 patients [Elektronische Daten] [John Messenger, S.Y. Chen, John Carroll, J.E.B. Burchenal, Kathy Kioussopoulos, Bertron Groves] Background: Current coronary angiographic techniques display complex three-dimensional (3D) coronary structures in two dimensions (2D). We have developed a 3D reconstruction (3DR) algorithm using standard single-plane angiographic images that allows for 3D display of coronary structures. The purpose of this study was to validate our 3DR algorithm and quantify anatomic characteristics of the right coronary artery (RCA) in vivo. Methods: Accuracy and reproducibility studies were performed using 3DRs of a coronary phantom and in vivo following 3DRs in 40 patients. The anatomic features of the RCA were then quantified in 100 patients. Results: Comparison of length and bifurcation angles (BA) from the phantom to the 3DRs revealed good accuracy and correlation for both (r = 0.95 and 0.93 respectively), with diameter error of <7%. In vivo, the average root mean square (RMS) error in the spatial coordinates of the vessel centerlines was 3.12 ± 0.77 and 3.16 ± 0.75 mm in 20 left coronary arteries (LCA) and 20 RCAs respectively. Interobserver average RMS error was 3.47 ± 1.96 mm and intraobserver average RMS error was 3.02 ± 1.07 and 3.44 ± 1.57 mm for two different operators (p = NS). The average RCA length was 10.2 ± 1.7 cm, average radius of curvature (ROC) was 52 ± 9°, and the average 3D bifurcation angle of the posterior descending artery (PDA) from the RCA was 55 ± 22°. Foreshortening (FS) of the segments of the RCA in three 'standard' projections ranged from 0-60, 0-75, and 0-82% respectively. Conclusions: Using our 3DR algorithm patient-specific anatomic characteristics can be accurately displayed and quantified, expanding the information that can be derived from routine coronary angiography. Kluwer Academic Publishers, 2000 coronary angiography nationallicence coronary arteries nationallicence image processing (computer-assisted) nationallicence three-dimensional reconstruction nationallicence Messenger John Denver V A Medical Center, Denver, Colorado, USA aut Chen S.Y. Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA aut Carroll John Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA aut Burchenal J.E.B. Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA aut Kioussopoulos Kathy Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA aut Groves Bertron Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA aut The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/6(2000-12-01), 413-427 0167-9899 16:6<413 2000 16 10554 https://doi.org/10.1023/A:1010643426720 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1010643426720 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Messenger John Denver V A Medical Center, Denver, Colorado, USA aut NATIONALLICENCE 700 1- Chen S.Y. Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA aut NATIONALLICENCE 700 1- Carroll John Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA aut NATIONALLICENCE 700 1- Burchenal J.E.B. Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA aut NATIONALLICENCE 700 1- Kioussopoulos Kathy Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA aut NATIONALLICENCE 700 1- Groves Bertron Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA aut NATIONALLICENCE 773 0- The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/6(2000-12-01), 413-427 0167-9899 16:6<413 2000 16 10554 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer