caa a22 4500 475791541 CHVBK 20180406123712.0 cr unu---uuuuu 170329e20000801xx s 000 0 eng 10.1023/A:1026541122010 doi (NATIONALLICENCE)springer-10.1023/A:1026541122010 Comparison of methods of fractional area change for detection of regional left ventricular dysfunction [Elektronische Daten] [Steen Carstensen, Ulla Hoest, Lars Kjoeller-Hansen, Kari Saunamäki, Dan Atar, Henning Kelbæk] Three methods for assessment of fractional area change (FAC) and conventional versus cross-sectional segmentation were compared under conditions known to occur frequently during stress echocardiography. Quantitative analysis of 80 echocardiograms obtained from healthy subjects, patients with left ventricular (LV) dysfunction and after coronary artery bypass grafting included segmental and cross-sectional FACs by the centroid method with fixed and floating reference and a method with floating external reference. All segmental and cross-sectional FACs were equally sensitive to LV dysfunction, and segmental FACs failed to accurately predict the location of coronary lesions. The centroid method with floating reference and cross-sectional FACs were the least affected by surgery induced intrathoracic heart motion. In moderate to severe LV dysfunction FAC by the centroid method with floating reference and cross sections were rarely within normal limits. Cross-sectional FACs may prove to be useful in stress echocardiography. For viability studies segmental FAC by fixed reference appears to be the method of choice. Kluwer Academic Publishers, 2000 echocardiography nationallicence quantitative nationallicence regional left ventricular function nationallicence Carstensen Steen Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut Hoest Ulla Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut Kjoeller-Hansen Lars Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut Saunamäki Kari Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut Atar Dan Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut Kelbæk Henning Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/4(2000-08-01), 257-266 0167-9899 16:4<257 2000 16 10554 https://doi.org/10.1023/A:1026541122010 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1026541122010 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Carstensen Steen Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut NATIONALLICENCE 700 1- Hoest Ulla Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut NATIONALLICENCE 700 1- Kjoeller-Hansen Lars Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut NATIONALLICENCE 700 1- Saunamäki Kari Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut NATIONALLICENCE 700 1- Atar Dan Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut NATIONALLICENCE 700 1- Kelbæk Henning Department of Medicine B, The Heart Centre at Rigshospitalet, University of Copenhagen, Denmark aut NATIONALLICENCE 773 0- The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/4(2000-08-01), 257-266 0167-9899 16:4<257 2000 16 10554 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer