caa a22 4500 475791665 CHVBK 20180406123712.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1023/A:1026540809758 doi (NATIONALLICENCE)springer-10.1023/A:1026540809758 Three-dimensional echocardiographic measurement of left ventricular mass: Comparison with magnetic resonance imaging and two-dimensional echocardiographic determinations in man [Elektronische Daten] [Michael Chuang, Raymond Beaudin, Marilyn Riley, Matthew Mooney, Warren Manning, Pamela Douglas, Mark Hibberd] This study was performed to compare a novel three-dimensional echocardiography (3DE) system to clinical two-dimensional echocardiography (2DE) and magnetic resonance imaging (MRI) for determination of left ventricular mass (LVM) in humans. LVM is an independent predictor of cardiac morbidity and mortality. Echocardiography is the most widely used clinical method for assessment of LVM, as it is non-invasive, portable and relatively inexpensive. However, when measuring LVM, 2DE is limited by assumptions about ventricular shape which do not affect 3D echo. Methods: A total of 25 unselected patients underwent 3DE, 2DE and MRI. Three-dimensional echo used a magnetic scanhead tracker allowing unrestricted selection and combination of images from multiple acoustic windows. Mass by quantitative 2DE was assessed using seven different geometric formulas. Results: LVM by MRI ranged from 91 to 316 g. There was excellent agreement between 3DE and MRI (r = 0.99, SEE = 6.9 g). Quantitative 2D methods correlated well with but underestimated MRI (r = 0.84-0.92) with SEEs over threefold greater (22.5-30.8 g). Interobserver variation was 7.6% for 3DE vs. 17.7% for 2DE. Conclusions: LVM in humans can be measured accurately, relative to MRI, by transthoracic 3D echo using magnetic tracking. Compared to 2D echo, 3D echocardiography significantly improves accuracy and reproducibility. Kluwer Academic Publishers, 2000 3D echocardiography nationallicence LV mass nationallicence LV volumes nationallicence magnetic resonance imaging nationallicence Chuang Michael Cardiovascular Division, Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of Medicine, MA, USA aut Beaudin Raymond Hewlett-Packard Company, Andover, MA, USA aut Riley Marilyn Cardiovascular Division, Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of Medicine, MA, USA aut Mooney Matthew Hewlett-Packard Company, Andover, MA, USA aut Manning Warren Cardiovascular Division, Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of Medicine, MA, USA aut Douglas Pamela Cardiovascular Division, Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of Medicine, MA, USA aut Hibberd Mark Cardiovascular Division, Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of Medicine, MA, USA aut The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/5(2000-10-01), 347-357 0167-9899 16:5<347 2000 16 10554 https://doi.org/10.1023/A:1026540809758 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1026540809758 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chuang Michael Cardiovascular Division, Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of Medicine, MA, USA aut NATIONALLICENCE 700 1- Beaudin Raymond Hewlett-Packard Company, Andover, MA, USA aut NATIONALLICENCE 700 1- Riley Marilyn Cardiovascular Division, Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of Medicine, MA, USA aut NATIONALLICENCE 700 1- Mooney Matthew Hewlett-Packard Company, Andover, MA, USA aut NATIONALLICENCE 700 1- Manning Warren Cardiovascular Division, Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of Medicine, MA, USA aut NATIONALLICENCE 700 1- Douglas Pamela Cardiovascular Division, Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of Medicine, MA, USA aut NATIONALLICENCE 700 1- Hibberd Mark Cardiovascular Division, Charles A. Dana Research Institute and the Harvard-Thorndike Laboratory of Medicine, MA, USA aut NATIONALLICENCE 773 0- The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/5(2000-10-01), 347-357 0167-9899 16:5<347 2000 16 10554 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer