caa a22 4500 475791673 CHVBK 20180406123712.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1023/A:1026532425842 doi (NATIONALLICENCE)springer-10.1023/A:1026532425842 Safety of EBCT contrast injection studies in severe pulmonary hypertension [Elektronische Daten] [Ronald Oudiz, Matthew Budoff, Bruce Brundage] Purpose:There is considerable literature published on noninvasive contrast-enhanced techniques to diagnose pulmonary vascular abnormalities, however little data exists on the safety of contrast injections in patients with elevated pulmonary arterial pressures. We studied the safety of contrast-enhanced electron beam computed tomography (EBCT) in 29 patients with severe pulmonary hypertension. The mean dose of intravenous contrast used was 124 ± 39 cc. Materials and methods:Subjects underwent EBCT using contrast injected at a rate of 2-4 ml/s. All patients were watched closely for at least 15 min post-procedure prior to being released. Patients had Doppler echocardiograms to estimate pulmonary artery pressure. Right heart catheterization data was collected for patients in which echocardiographic data was unavailable. Results:A total of 29 patients with pulmonary arterial hypertension were studied. There were 17 patients with primary pulmonary hypertension (PPH), and 12 patients with secondary forms of pulmonary hypertension. None of the patients developed complications from their study. Conclusion:There is a paucity of data on the safety of contrast injections in patients with severely elevated pulmonary arterial pressures. Contrast-enhanced EBCT was well-tolerated in our diverse series of patients with severely elevated pulmonary arterial pressures. Clinicians concerned about invasive pulmonary angiography should consider contrast-enhanced EBCT as a safe alternative to angiography. Kluwer Academic Publishers, 2000 contrast nationallicence pulmonary hypertension nationallicence safety nationallicence Oudiz Ronald Harbor-UCLA Medical Center, Saint John's Cardiovascular Research Institute, Torrance, California, USA aut Budoff Matthew Harbor-UCLA Medical Center, Saint John's Cardiovascular Research Institute, Torrance, California, USA aut Brundage Bruce Bend Memorial Clinic, Bend, Oregon, USA aut The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/5(2000-10-01), 399-403 0167-9899 16:5<399 2000 16 10554 https://doi.org/10.1023/A:1026532425842 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1026532425842 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Oudiz Ronald Harbor-UCLA Medical Center, Saint John's Cardiovascular Research Institute, Torrance, California, USA aut NATIONALLICENCE 700 1- Budoff Matthew Harbor-UCLA Medical Center, Saint John's Cardiovascular Research Institute, Torrance, California, USA aut NATIONALLICENCE 700 1- Brundage Bruce Bend Memorial Clinic, Bend, Oregon, USA aut NATIONALLICENCE 773 0- The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/5(2000-10-01), 399-403 0167-9899 16:5<399 2000 16 10554 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer