caa a22 4500 475791800 CHVBK 20180406123713.0 cr unu---uuuuu 170329e20000401xx s 000 0 eng 10.1023/A:1006304626233 doi (NATIONALLICENCE)springer-10.1023/A:1006304626233 Adipose replacement and wall motion abnormalities in right ventricle arrhythmias: evaluation by MR imaging. Retrospective evaluation on 124 patients [Elektronische Daten] [Giuseppe Molinari, Francesco Sardanelli, Franco Zandrino, Roberto Parodi, Giovanni Bertero, Elena Richiardi, Paolo Donna, Fiorenzo Gaita, Maria Masperone] We reevaluated the magnetic resonance (MR) examinations of 38 healthy volunteers (control group, CG) and of 124 patients with RV arrhythmia with left bundle branch block (LBBB) morphology: 45 with episodes of RV sustained tachycardia and of polymorphic RV premature beats (RVST-PPB group); 36 with only RV outflow tract sustained or not sustained tachycardia (RVOTT group); 43 with RV monomorphic premature beats (RVMPB group). All the examinations were reevaluated in a blinded fashion for detecting myocardial adipose replacement (AR) and wall bulges or aneurysms. In RVST-PPB patients, no AR was observed in 9%; 1 RV region involvement, 0%; 2 regions, 4%; ≥3 regions, 87%; left ventricle (LV), 15%. RVOTT patients: 0%, 53%, 14%, 5%, and 28%, respectively. RVMPB patients: 0%, 46%, 19%, 2%, and 33%, respectively. In CG, AR was observed in 11% (in RV outflow tract). RV bulges were detected in 80% of RVST-PPB, 39% of RVOTT, and 14% of RVMPB patients, none of the CG; RV aneurysms in 33% of RVST-PPB patients, none of RVOTT patients, RVMBP patients, and CG. A significant difference among groups for RV and LV AR as well as RV bulges and aneurysms was found (p < 0.0001). In the direct comparisons, significant differences were found for: disease duration (RVST-PPB vs. RVMPB, p = 0.0396); RV AR (all the patients groups vs. CG, RVST-PPB vs. RVOTT or RVMPB, p < 0.0001); RV aneurysms (RVST-PPB vs. CG, RVST-PPB vs. RVOTT or RVMPB, p < 0.0002); bulges (all comparisons, p < 0.0174). AR is confirmed as a structural substrate in RV arrhythmias. Number and extension of MR abnormalities are correlated to different degrees of RV arrhythmias. Kluwer Academic Publishers, 2000 arrhythmogenic right ventricular cardiomyopathy nationallicence heart nationallicence magnetic resonance nationallicence right ventricle arrhythmyas nationallicence Molinari Giuseppe Department of Cardiology, University of Genoa, Italy aut Sardanelli Francesco Department of Diagnostic Imaging, University of Genoa, Italy aut Zandrino Franco Department of Diagnostic Imaging, University of Genoa, Italy aut Parodi Roberto Department of Diagnostic Imaging, University of Genoa, Italy aut Bertero Giovanni Department of Cardiology, University of Genoa, Italy aut Richiardi Elena Department of Cardiology, Hospital of Asti, Italy aut Donna Paolo Department of Cardiology, Hospital of Asti, Italy aut Gaita Fiorenzo Department of Cardiology, Hospital of Asti, Italy aut Masperone Maria Department of Cardiology, University of Genoa, Italy aut The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/2(2000-04-01), 105-115 0167-9899 16:2<105 2000 16 10554 https://doi.org/10.1023/A:1006304626233 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1006304626233 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Molinari Giuseppe Department of Cardiology, University of Genoa, Italy aut NATIONALLICENCE 700 1- Sardanelli Francesco Department of Diagnostic Imaging, University of Genoa, Italy aut NATIONALLICENCE 700 1- Zandrino Franco Department of Diagnostic Imaging, University of Genoa, Italy aut NATIONALLICENCE 700 1- Parodi Roberto Department of Diagnostic Imaging, University of Genoa, Italy aut NATIONALLICENCE 700 1- Bertero Giovanni Department of Cardiology, University of Genoa, Italy aut NATIONALLICENCE 700 1- Richiardi Elena Department of Cardiology, Hospital of Asti, Italy aut NATIONALLICENCE 700 1- Donna Paolo Department of Cardiology, Hospital of Asti, Italy aut NATIONALLICENCE 700 1- Gaita Fiorenzo Department of Cardiology, Hospital of Asti, Italy aut NATIONALLICENCE 700 1- Masperone Maria Department of Cardiology, University of Genoa, Italy aut NATIONALLICENCE 773 0- The International Journal of Cardiac Imaging Kluwer Academic Publishers 16/2(2000-04-01), 105-115 0167-9899 16:2<105 2000 16 10554 Metadata rights reserved Springer special CC-BY-NC licence nationallicence SWISSBIB 475791355 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer