caa a22 4500 475796616 CHVBK 20180406123726.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/s001220051348 doi (NATIONALLICENCE)springer-10.1007/s001220051348 A- or C-chromosomes, does it matter for the transfer of transgenes from Brassica napus [Elektronische Daten] [J. Tomiuk, T. P. Hauser, R. Bagger-Jørgensen] Abstract.: Introgression of genes from allotetraploid Brassica napus into its diploid wild relative B. rapa is generally considered to be inevitable. As a means to minimize a potential ecological risk in environments where B. rapa is growing, the insertion of transgenes into chromosome regions of B. napus with a very low probability of transfer to backcross generations with B. rapa has been proposed. Recently, the progeny of four backcross generations between transgenic herbicide-tolerant B. napus and B. rapa was studied in selection experiments (Metz et al. 1997). The rapid decrease in the frequency of herbicide-tolerant plants was explained by selection against the C-chromosomes of B. napus in favor of the homeologous A-chromosomes. Obviously, such C-chromosomes could be potential candidates as safe integration sites for transgenes. We considered these safety aspects using a simple population genetic model. Theory and experiments, however, do not favor the chromosomes of B. napus as safe candidates with respect to the introgression of transgenes into wild populations of B. rapa. Springer-Verlag Berlin Heidelberg, 2000 Key words Safe integration nationallicence Chromosome variation nationallicence Oilseed rape nationallicence Gene transfer nationallicence Risk assessment, Brassica rapa nationallicence Tomiuk J. Department of Plant Biology and Biogeochemistry, Risø National Laboratory, P.O. Box 49, DK-4000 Roskilde, Denmark, DK aut Hauser T. P. Botanical Institute, University of Copenhagen, Øster Farimagsgade 2D, DK-1353 Copenhagen, Denmark, DK aut Bagger-Jørgensen R. Department of Plant Biology and Biogeochemistry, Risø National Laboratory, P.O. Box 49, DK-4000 Roskilde, Denmark, DK aut https://doi.org/10.1007/s001220051348 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s001220051348 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tomiuk J. Department of Plant Biology and Biogeochemistry, Risø National Laboratory, P.O. Box 49, DK-4000 Roskilde, Denmark, DK aut NATIONALLICENCE 700 1- Hauser T. P. Botanical Institute, University of Copenhagen, Øster Farimagsgade 2D, DK-1353 Copenhagen, Denmark, DK aut NATIONALLICENCE 700 1- Bagger-Jørgensen R. Department of Plant Biology and Biogeochemistry, Risø National Laboratory, P.O. Box 49, DK-4000 Roskilde, Denmark, DK aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer