caa a22 4500 475799534 CHVBK 20180406123733.0 cr unu---uuuuu 170329e20001101xx s 000 0 eng 10.1023/A:1010298701251 doi (NATIONALLICENCE)springer-10.1023/A:1010298701251 Mapping Quantitative Trait Loci for Circadian Behavioral Rhythms in SMXA Recombinant Inbred Strains [Elektronische Daten] [Tohru Suzuki, Akira Ishikawa, Masahiko Nishimura, Takashi Yoshimura, Takao Namikawa, Shizufumi Ebihara] SM/J and A/J inbred strain of mice have different characteristics in circadian behaviors such as free-running period (τ), phase relationship (ψ) between light-dark cycles and activity rhythms, and amount of wheel-running activity. To determine the genes which affect these behaviors, a quantitative trait locus (QTL) analysis using SMXA recombinant inbred strains derived from SM/J and A/J mice was performed. Concerning τ, two regions on chromosomes (Chrs) 7 and 18 surpassed the genome-wide suggestive level. As for ψ, one suggestive QTL was detected on Chr 7. The QTLs which affect daily activity counts under light-dark cycles and constant darkness were mapped to the same chromosomal regions on Chrs 1 and 17, respectively. The provisional QTLs detected in the present study might be useful for understanding the complex mechanism regulating circadian behaviors. Plenum Publishing Corporation, 2000 SM/J mice nationallicence A/J mice nationallicence SMXA recombinant inbred strains nationallicence quantitative trait locus nationallicence circadian rhythm nationallicence Suzuki Tohru Division of Biomodeling, Graduate School of Bioagricultural Sciences, Nagoya University, 464-8601, Nagoya, Japan aut Ishikawa Akira Division of Genetics and Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, 464-8601, Nagoya, Japan aut Nishimura Masahiko Institute for Laboratory Animal Research, Nagoya University School of Medicine, 466-8550, Nagoya, Japan aut Yoshimura Takashi Division of Biomodeling, Graduate School of Bioagricultural Sciences, Nagoya University, 464-8601, Nagoya, Japan aut Namikawa Takao Division of Genetics and Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, 464-8601, Nagoya, Japan aut Ebihara Shizufumi Division of Biomodeling, Graduate School of Bioagricultural Sciences, Nagoya University, 464-8601, Nagoya, Japan aut Behavior Genetics Kluwer Academic Publishers-Plenum Publishers 30/6(2000-11-01), 447-453 0001-8244 30:6<447 2000 30 10519 https://doi.org/10.1023/A:1010298701251 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1010298701251 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Suzuki Tohru Division of Biomodeling, Graduate School of Bioagricultural Sciences, Nagoya University, 464-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Ishikawa Akira Division of Genetics and Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, 464-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Nishimura Masahiko Institute for Laboratory Animal Research, Nagoya University School of Medicine, 466-8550, Nagoya, Japan aut NATIONALLICENCE 700 1- Yoshimura Takashi Division of Biomodeling, Graduate School of Bioagricultural Sciences, Nagoya University, 464-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Namikawa Takao Division of Genetics and Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, 464-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Ebihara Shizufumi Division of Biomodeling, Graduate School of Bioagricultural Sciences, Nagoya University, 464-8601, Nagoya, Japan aut NATIONALLICENCE 773 0- Behavior Genetics Kluwer Academic Publishers-Plenum Publishers 30/6(2000-11-01), 447-453 0001-8244 30:6<447 2000 30 10519 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer