caa a22 4500 475799836 CHVBK 20180406123734.0 cr unu---uuuuu 170329e20000701xx s 000 0 eng 10.1023/A:1026597300525 doi (NATIONALLICENCE)springer-10.1023/A:1026597300525 Natal Dispersal in Rhesus Macaques Is Related to Serotonin Transporter Gene Promoter Variation [Elektronische Daten] [Andrea Trefilov, John Berard, Michael Krawczak, Jörg Schmidtke] A VNTR polymorphism previously characterized in the promoter region of the human serotonin transporter (SLC6A4) gene was also found to segregate two major alleles (l and s) among the free-ranging rhesus macaques of Cayo Santiago, Puerto Rico. When VNTR genotypes were related to age at male natal dispersal on Cayo Santiago, ss homozygotes (43 of 532 males tested) were found to have left their natal groups significantly earlier (age 57.1 ± 2.6 months) than carriers of the l allele (ll age, 71.5 ± 2.1 months; ls age, 63.5 ± 1.5 months; P = 0.0001). Since migration implies reproductive costs and benefits that change with age at dispersal, migration at an intermediate age might have conferred a heterozygote advantage serving to maintain the VNTR polymorphism via overdominant selection. Plenum Publishing Corporation, 2000 Serotonin transporter (SLC6A4) gene nationallicence promoter polymorphism nationallicence age at natal dispersal nationallicence rhesus macaques nationallicence Trefilov Andrea Institute of Human Genetics, Hannover Medical School, Carl-Neuberg-Strasse 1, D-30625, Hannover, Germany aut Berard John Caribbean Primate Research Center, University of Puerto Rico Medical Sciences Campus, P.O. Box 906, 00741, Punta Santiago, Puerto Rico, USA aut Krawczak Michael Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, CF14 4XN, Cardiff, UK aut Schmidtke Jörg Institute of Human Genetics, Hannover Medical School, Carl-Neuberg-Strasse 1, D-30625, Hannover, Germany aut Behavior Genetics Kluwer Academic Publishers-Plenum Publishers 30/4(2000-07-01), 295-301 0001-8244 30:4<295 2000 30 10519 https://doi.org/10.1023/A:1026597300525 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1026597300525 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Trefilov Andrea Institute of Human Genetics, Hannover Medical School, Carl-Neuberg-Strasse 1, D-30625, Hannover, Germany aut NATIONALLICENCE 700 1- Berard John Caribbean Primate Research Center, University of Puerto Rico Medical Sciences Campus, P.O. Box 906, 00741, Punta Santiago, Puerto Rico, USA aut NATIONALLICENCE 700 1- Krawczak Michael Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, CF14 4XN, Cardiff, UK aut NATIONALLICENCE 700 1- Schmidtke Jörg Institute of Human Genetics, Hannover Medical School, Carl-Neuberg-Strasse 1, D-30625, Hannover, Germany aut NATIONALLICENCE 773 0- Behavior Genetics Kluwer Academic Publishers-Plenum Publishers 30/4(2000-07-01), 295-301 0001-8244 30:4<295 2000 30 10519 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer