caa a22 4500 475799933 CHVBK 20180406123734.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1023/A:1001967019229 doi (NATIONALLICENCE)springer-10.1023/A:1001967019229 Nesting Behavior of House Mice (Mus Domesticus) Selected for Increased Wheel-Running Activity [Elektronische Daten] [Patrick Carter, John Swallow, Sarah Davis, Theodore Garland Jr] Nest building was measured in "active” (housed with access to running wheels) and "sedentary” (without wheel access) mice (Mus domesticus) from four replicate lines selected for 10 generations for high voluntary wheel-running behavior, and from four randombred control lines. Based on previous studies of mice bidirectionally selected for thermoregulatory nest building, it was hypothesized that nest building would show a negative correlated response to selection on wheel-running. Such a response could constrain the evolution of high voluntary activity because nesting has also been shown to be positively genetically correlated with successful production of weaned pups. With wheel access, selected mice of both sexes built significantly smaller nests than did control mice. Without wheel access, selected females also built significantly smaller nests than did control females, but only when body mass was excluded from the statistical model, suggesting that body mass mediated this correlated response to selection. Total distance run and mean running speed on wheels was significantly higher in selected mice than in controls, but no differences in amount of time spent running were measured, indicating a complex cause of the response of nesting to selection for voluntary wheel running. Plenum Publishing Corporation, 2000 Artificial selection nationallicence evolutionary constraint nationallicence correlated response nationallicence genetic correlation nationallicence nesting behavior nationallicence wheel-running behavior nationallicence Carter Patrick School of Biological Sciences, Washington State University, 99164-4236, Pullman, WA, USA aut Swallow John Department of Zoology, University of Maryland, College Park, 20742, MD, USA aut Davis Sarah aut Garland Jr Theodore aut Behavior Genetics Kluwer Academic Publishers-Plenum Publishers 30/2(2000-03-01), 85-94 0001-8244 30:2<85 2000 30 10519 https://doi.org/10.1023/A:1001967019229 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1001967019229 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Carter Patrick School of Biological Sciences, Washington State University, 99164-4236, Pullman, WA, USA aut NATIONALLICENCE 700 1- Swallow John Department of Zoology, University of Maryland, College Park, 20742, MD, USA aut NATIONALLICENCE 700 1- Davis Sarah aut NATIONALLICENCE 700 1- Garland Jr Theodore aut NATIONALLICENCE 773 0- Behavior Genetics Kluwer Academic Publishers-Plenum Publishers 30/2(2000-03-01), 85-94 0001-8244 30:2<85 2000 30 10519 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer