caa a22 4500 475801296 CHVBK 20180406123738.0 cr unu---uuuuu 170329e20000101xx s 000 0 eng 10.1007/s002689910017 doi (NATIONALLICENCE)springer-10.1007/s002689910017 Therapeutic Splenectomy in Immune Thrombocytopenic Purpura [Elektronische Daten] [Nazir A. Wani, Fazal Q. Parray] The effects of splenectomy in 41 patients managed from 1982 to 1995 at Sher-i-Kashmir Institute of Medical Sciences, Srinagar (Jammu and Kashmir), India, were studied. Immune thrombocytopenic purpura (ITP) was the main indication for therapeutic splenectomy among all the hematologic disorders. The mean age was 30 years (range 7-64), and the male to female ratio was 1.05:1. The mean platelet count in the preoperative period was 31,751/mm3 (range 4000-85,000). All patients presented with thrombocytopenia, i.e., platelet count of <100,000/mm3. In addition, 5 patients presented with anemia, i.e., Hb <10 g%. Among the patients with thrombocytopenia, 30 patients presented with counts <50,000/mm3 and 11 patients presented with counts between 50,000-100,000/mm3. None of the patients presented with leukopenia. The morbidity observed was 15% and mortality was 2%. The response to splenectomy was complete for thrombocytopenia in 3 patients and partial in 5 patients; 4 patients failed to show any response. In anemic patients, 4 patients showed complete response and 1 patient showed no response. The prognosis was excellent in patients with platelet count >50,000/mm3, age <50 years, no concomitant disease, and disease of shorter duration. by the Société Internationale de Chirurgie, 2000 Wani Nazir A. Department of Surgery, Sher-i-Kashmir Institute of Medical Sciences, GPO Post Bag No. 27, Soura, Srinagar-190 011, Kashmir, India, IN aut Parray Fazal Q. Department of Surgery, Sher-i-Kashmir Institute of Medical Sciences, GPO Post Bag No. 27, Soura, Srinagar-190 011, Kashmir, India, IN aut World Journal of Surgery Springer-Verlag 24/1(2000-01-01), 92-94 0364-2313 24:1<92 2000 24 268 https://doi.org/10.1007/s002689910017 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689910017 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wani Nazir A. Department of Surgery, Sher-i-Kashmir Institute of Medical Sciences, GPO Post Bag No. 27, Soura, Srinagar-190 011, Kashmir, India, IN aut NATIONALLICENCE 700 1- Parray Fazal Q. Department of Surgery, Sher-i-Kashmir Institute of Medical Sciences, GPO Post Bag No. 27, Soura, Srinagar-190 011, Kashmir, India, IN aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/1(2000-01-01), 92-94 0364-2313 24:1<92 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer