caa a22 4500 475801466 CHVBK 20180406123738.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s002689910118 doi (NATIONALLICENCE)springer-10.1007/s002689910118 Effect of Laparoscopic Cholecystectomy on Platelet Aggregation [Elektronische Daten] [Serdar Yol, Adil Kartal, Ümran Çalişkan, Şakir Tavli, Mustafa Şahin, Mikdat Bozer] Abstract.: The purpose of this study was to investigate the effect of laparoscopic cholecystectomy on platelet function. We operated on 40 women with symptomatic gallbladder stone, 20 of whom (study group) underwent laparoscopic cholecystectomy and 20 of whom (control group) open cholecystectomy. Patients with a history of bleeding, abnormal platelet count, or systemic disorders and those who were on salicylates, heparin, or oral anticoagulants were excluded. Blood parameters were checked at the beginning and the end of the operation, including platelet aggregation using adenosine 5′-diphosphate (ADP), collagen, and ristocetin in a whole-blood aggregometer. Platelet aggregation was evaluated by percent aggregation. Platelet aggregation due to collagen and ristocetin increased significantly at the end of the operation in the study group (p < 0.001). Aggregation due to ADP did not differ significantly from the start to the end of the operation. Control group results did not show any differences. Although the clinical findings of aggregated platelet are not frequently observed in practice, we suggest that laparoscopy increases platelet aggregation. 2000 by the Société Internationale de Chir, 2000 Yol Serdar Department of General Surgery, Selçuk University Faculty of Medicine, Akyokuş-Konya 42080, Turkey, Turkey aut Kartal Adil Department of General Surgery, Selçuk University Faculty of Medicine, Akyokuş-Konya 42080, Turkey, Turkey aut Çalişkan Ümran Department of Pediatric Hematology, Selçuk University Faculty of Medicine, Akyokuş-Konya 42080, Turkey, Turkey aut Tavli Şakir Department of General Surgery, Selçuk University Faculty of Medicine, Akyokuş-Konya 42080, Turkey, Turkey aut Şahin Mustafa Department of General Surgery, Selçuk University Faculty of Medicine, Akyokuş-Konya 42080, Turkey, Turkey aut Bozer Mikdat Department of General Surgery, Harran University Faculty of Medicine, Şanhurfa 63100, Turkey, Turkey aut World Journal of Surgery Springer-Verlag 24/6(2000-06-01), 734-738 0364-2313 24:6<734 2000 24 268 https://doi.org/10.1007/s002689910118 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689910118 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yol Serdar Department of General Surgery, Selçuk University Faculty of Medicine, Akyokuş-Konya 42080, Turkey, Turkey aut NATIONALLICENCE 700 1- Kartal Adil Department of General Surgery, Selçuk University Faculty of Medicine, Akyokuş-Konya 42080, Turkey, Turkey aut NATIONALLICENCE 700 1- Çalişkan Ümran Department of Pediatric Hematology, Selçuk University Faculty of Medicine, Akyokuş-Konya 42080, Turkey, Turkey aut NATIONALLICENCE 700 1- Tavli Şakir Department of General Surgery, Selçuk University Faculty of Medicine, Akyokuş-Konya 42080, Turkey, Turkey aut NATIONALLICENCE 700 1- Şahin Mustafa Department of General Surgery, Selçuk University Faculty of Medicine, Akyokuş-Konya 42080, Turkey, Turkey aut NATIONALLICENCE 700 1- Bozer Mikdat Department of General Surgery, Harran University Faculty of Medicine, Şanhurfa 63100, Turkey, Turkey aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/6(2000-06-01), 734-738 0364-2313 24:6<734 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer