caa a22 4500 475801474 CHVBK 20180406123738.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s002689910109 doi (NATIONALLICENCE)springer-10.1007/s002689910109 Metabolic Management of Patients with Severe Burns [Elektronische Daten] [Robert H. Demling, Patrick Seigne] Abstract.: Burn injury results in profound metabolic abnormalities perpetuated by an exaggerated stress response to injury. Hypermetabolism and marked catabolism, with rapid erosion of lean body mass, becomes evident shortly after injury. Much of the morbidity and mortality of a major burn can be attributed to this process, which increases infection risks, decreases the healing rate, and alters cell function. Rapid removal of devitalized burn tissue combined with early aggressive nutritional support significantly attenuates this autodestructive process. The addition of anabolic agents decreases the degree of lean mass loss and increases the rate of restoration. Immediate attention to the metabolic response to a severe burn significantly decreases complications and improves outcome. 2000 by the Société Internationale de Chir, 2000 Demling Robert H. Department of Surgery, Burn Center, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, USA, USA aut Seigne Patrick Department of Anesthesia and Critical Care, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, USA, USA aut World Journal of Surgery Springer-Verlag 24/6(2000-06-01), 673-680 0364-2313 24:6<673 2000 24 268 https://doi.org/10.1007/s002689910109 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689910109 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Demling Robert H. Department of Surgery, Burn Center, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, USA, USA aut NATIONALLICENCE 700 1- Seigne Patrick Department of Anesthesia and Critical Care, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, USA, USA aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/6(2000-06-01), 673-680 0364-2313 24:6<673 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer