caa a22 4500 475801601 CHVBK 20180406123738.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s002689910106 doi (NATIONALLICENCE)springer-10.1007/s002689910106 Wound Healing Associated with Severe Surgical Illness [Elektronische Daten] [Matthew A. Clark, Lindsay D. Plank, Graham L. Hill] Abstract.: Severe injury or infection is associated with a hypermetabolic response that, when excessive, results in impaired wound healing and as a consequence increased morbidity and mortality. The objective examination of wound healing in humans is difficult and generally requires the use of models. Evidence is accumulating that nutritional and growth factors play important roles in improving the wound healing response, particularly after thermal injury and uncomplicated major surgery. The septic patient represents the biggest challenge to those seeking to optimize wound healing capacity. Advances in molecular biology have provided promising therapies in experimental studies of wound healing that await clinical investigation. 2000 by the Société Internationale de Chir, 2000 Clark Matthew A. University Department of Surgery, Auckland Hospital, Fifth Floor, Private Bag 92-024, Auckland 1003, New Zealand, New Zealand aut Plank Lindsay D. University Department of Surgery, Auckland Hospital, Fifth Floor, Private Bag 92-024, Auckland 1003, New Zealand, New Zealand aut Hill Graham L. University Department of Surgery, Auckland Hospital, Fifth Floor, Private Bag 92-024, Auckland 1003, New Zealand, New Zealand aut World Journal of Surgery Springer-Verlag 24/6(2000-06-01), 648-654 0364-2313 24:6<648 2000 24 268 https://doi.org/10.1007/s002689910106 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689910106 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Clark Matthew A. University Department of Surgery, Auckland Hospital, Fifth Floor, Private Bag 92-024, Auckland 1003, New Zealand, New Zealand aut NATIONALLICENCE 700 1- Plank Lindsay D. University Department of Surgery, Auckland Hospital, Fifth Floor, Private Bag 92-024, Auckland 1003, New Zealand, New Zealand aut NATIONALLICENCE 700 1- Hill Graham L. University Department of Surgery, Auckland Hospital, Fifth Floor, Private Bag 92-024, Auckland 1003, New Zealand, New Zealand aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/6(2000-06-01), 648-654 0364-2313 24:6<648 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer