caa a22 4500 475802020 CHVBK 20180406123740.0 cr unu---uuuuu 170329e20000701xx s 000 0 eng 10.1007/s002680010138 doi (NATIONALLICENCE)springer-10.1007/s002680010138 Effects of Proximal Duodenal Transection and Anastomosis on Interdigestive Sphincter of Oddi Cyclic Motility in Conscious Dogs [Elektronische Daten] [Zhou-Lu Deng, Toshinaga Nabae, Hiroyuki Konomi, Shunichi Takahata, Kazunori Yokohata, Yoshiaki Ogawa, Kazuo Chijiiwa, Masao Tanaka] Abstract.: Gallstones formed after gastrectomy are bilirubinate stones probably associated with biliary stasis and infection. Effects of proximal duodenal transection performed during gastrectomy on interdigestive sphincter of Oddi cyclic motility possibly relevant to this phenomenon were investigated in four conscious dogs. Although the cyclic change in sphincter motility was still in concert with the duodenal migrating motor complex after duodenal transection, the mean period was shortened (p < 0.02), and the frequency (p < 0.005) and amplitude (p < 0.001) of sphincter phasic waves during phase III were decreased. The cyclic variation of basal pressure disappeared, and the mean basal pressure throughout the cycle was significantly reduced (p < 0.003). Transient inhibition of sphincter and duodenal contractions normally seen during phase III disappeared. Duodenal transection reversed the response of the sphincter to cholecystokinin-octapeptide from inhibition to stimulation and from reduction of the basal pressure to elevation. These data suggest that duodenal transection produces significant changes in interdigestive sphincter of Oddi motility, possibly contributing to augmented duodenobiliary reflux and then lithogenesis. Myoneural continuity between the stomach and sphincter of Oddi at the proximal duodenum may play an important role in maintaining normal biliary dynamics. by Société Internionale de Chirurgie, 2000 Deng Zhou-Lu Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut Nabae Toshinaga Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut Konomi Hiroyuki Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut Takahata Shunichi Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut Yokohata Kazunori Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut Ogawa Yoshiaki Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut Chijiiwa Kazuo Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut Tanaka Masao Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut World Journal of Surgery Springer-Verlag 24/7(2000-07-01), 863-869 0364-2313 24:7<863 2000 24 268 https://doi.org/10.1007/s002680010138 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002680010138 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Deng Zhou-Lu Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut NATIONALLICENCE 700 1- Nabae Toshinaga Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut NATIONALLICENCE 700 1- Konomi Hiroyuki Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut NATIONALLICENCE 700 1- Takahata Shunichi Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut NATIONALLICENCE 700 1- Yokohata Kazunori Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut NATIONALLICENCE 700 1- Ogawa Yoshiaki Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut NATIONALLICENCE 700 1- Chijiiwa Kazuo Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut NATIONALLICENCE 700 1- Tanaka Masao Department of Surgery I, Kyushu University Faculty of Medicine, Fukuoka 812-8582, Japan, JP aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/7(2000-07-01), 863-869 0364-2313 24:7<863 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer