caa a22 4500 475802039 CHVBK 20180406123740.0 cr unu---uuuuu 170329e20000701xx s 000 0 eng 10.1007/s002680010137 doi (NATIONALLICENCE)springer-10.1007/s002680010137 Primary Gastric B Cell Lymphoma: Audit of 82 Cases Treated with Surgery and Classified According to the Concept of Mucosa-associated Lymphoid Tissue Lymphoma [Elektronische Daten] [Yasuhiro Kodera, Shigeo Nakamura, Yoshitaka Yamamura, Yasuhiro Shimizu, Akihito Torii, Takashi Hirai, Kenzo Yasui, Takeshi Morimoto, Tomoyuki Kato] Abstract.: There has been a trend toward stomach conservation during treatment for primary gastric lymphoma, but surgery ensures accurate pathologic diagnosis through the examination of resected specimens. A histopathologic classification for primary gastric lymphoma had been established with the knowledge that the low grade and high grade components occasionally coexist in a single lesion. Efficacy of this classification as an indicator of biologic behavior and prognosis was evaluated. The classification was performed by reexamining surgically resected specimens from 82 patients with stage IE and IIE gastric lymphoma. Clinical characteristics of the low grade and high grade lymphomas were then evaluated and the survival data analyzed. Despite the larger tumor diameter, the depth of invasion for the low grade type was mostly submucosal, and none had serosal invasion. In contrast, 50% of the high grade type had serosal involvement and were also found to have a higher incidence of node metastasis. Prognosis of the low grade type, a 10-year survival rate exceeding 90%, was significantly better than that of the high grade type. Multivariate analysis revealed that curability of the operation followed by the histopathologic grade were significant independent prognostic factors. Some characteristics of the low grade lymphoma were not consistent with what has been reported in the studies involving stomach-conserving strategies. Investigators are advised to note that the histopathologic grade determined with biopsy specimens alone could be misleading. by Société Internionale de Chirurgie, 2000 Kodera Yasuhiro Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut Nakamura Shigeo Department of Pathology and Clinical Laboratories, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut Yamamura Yoshitaka Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut Shimizu Yasuhiro Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut Torii Akihito Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut Hirai Takashi Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut Yasui Kenzo Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut Morimoto Takeshi Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut Kato Tomoyuki Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut World Journal of Surgery Springer-Verlag 24/7(2000-07-01), 857-862 0364-2313 24:7<857 2000 24 268 https://doi.org/10.1007/s002680010137 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002680010137 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kodera Yasuhiro Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut NATIONALLICENCE 700 1- Nakamura Shigeo Department of Pathology and Clinical Laboratories, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut NATIONALLICENCE 700 1- Yamamura Yoshitaka Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut NATIONALLICENCE 700 1- Shimizu Yasuhiro Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut NATIONALLICENCE 700 1- Torii Akihito Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut NATIONALLICENCE 700 1- Hirai Takashi Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut NATIONALLICENCE 700 1- Yasui Kenzo Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut NATIONALLICENCE 700 1- Morimoto Takeshi Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut NATIONALLICENCE 700 1- Kato Tomoyuki Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan, JP aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/7(2000-07-01), 857-862 0364-2313 24:7<857 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer