caa a22 4500 475802144 CHVBK 20180406123740.0 cr unu---uuuuu 170329e20001201xx s 000 0 eng 10.1007/s002680010274 doi (NATIONALLICENCE)springer-10.1007/s002680010274 Remaining Small Bowel Length: Association with Catheter Sepsis in Patients Receiving Home Total Parenteral Nutrition: Evidence of Bacterial Translocation [Elektronische Daten] [Ricardo M. Terra, Caio Plopper, Dan L. Waitzberg, Celso Cukier, Sérgio Santoro, Juliana R. Martins, Rubens J. Song, Joaquim Gama-Rodrigues] Patients with short bowel syndrome (SBS) receiving total parenteral nutrition (TPN) have a high incidence of catheter-related sepsis, one of its major complications. The aim of this study was to correlate the length of remaining small bowel (RSB) with septic episodes related to the central venous catheter in a group of patients with severe SBS with home TPN. The length of the RSB (<50 cm or ≥50 cm) was related to the frequency of catheter sepsis, time until the first episode, and the agents responsible in eight SBS patients receiving home TPN. There were 13 episodes of catheter infection (0.88 per patient-year). The group with a shorter RSB length (five patients) presented 1.3 to 2.76 infections/year and 2 to 9 months until the first episode, compared to 0 to 0.75 infections/year (p= 0.0357) and 11 to 65 months until the first episode (p= 0.0332) in the group with the longer RSB. In the first group, the agents isolated were Enterobacteriae (Enterobacter sp., Klebsiella sp., Pseudomonas sp., and Proteus sp.) in eight episodes and Candida sp. in one. In the latter sepsis was caused by Staphylococcus sp. in three episodes and Pseudomonas sp. in one. Therefore patients with remaining small bowel shorter than 50 cm have a higher frequency of catheter-related sepsis, particularly by enteric microorganisms. This might be an evidence of the occurrence of bacterial translocation and its role in the pathogenesis of catheter-related sepsis in patients with an extremely short RSB receiving home TPN. Société Internationale de Chirurgie, 2000 Terra Ricardo M. Faculty of Medicine, University of São Paulo, Al. Franca 555, 01422-010 São Paulo, SP, Brazil, BR aut Plopper Caio Faculty of Medicine, University of São Paulo, Al. Franca 555, 01422-010 São Paulo, SP, Brazil, BR aut Waitzberg Dan L. Department of Gastroenterology, Faculty of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, 01246-903, São Paulo, SP, Brazil, BR aut Cukier Celso Department of Gastroenterology, Faculty of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, 01246-903, São Paulo, SP, Brazil, BR aut Santoro Sérgio Department of Gastroenterology, Faculty of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, 01246-903, São Paulo, SP, Brazil, BR aut Martins Juliana R. Faculty of Medicine, University of São Paulo, Al. Franca 555, 01422-010 São Paulo, SP, Brazil, BR aut Song Rubens J. Faculty of Medicine, University of São Paulo, Al. Franca 555, 01422-010 São Paulo, SP, Brazil, BR aut Gama-Rodrigues Joaquim Department of Gastroenterology, Faculty of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, 01246-903, São Paulo, SP, Brazil, BR aut World Journal of Surgery Springer-Verlag 24/12(2000-12-01), 1537-1541 0364-2313 24:12<1537 2000 24 268 https://doi.org/10.1007/s002680010274 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002680010274 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Terra Ricardo M. Faculty of Medicine, University of São Paulo, Al. Franca 555, 01422-010 São Paulo, SP, Brazil, BR aut NATIONALLICENCE 700 1- Plopper Caio Faculty of Medicine, University of São Paulo, Al. Franca 555, 01422-010 São Paulo, SP, Brazil, BR aut NATIONALLICENCE 700 1- Waitzberg Dan L. Department of Gastroenterology, Faculty of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, 01246-903, São Paulo, SP, Brazil, BR aut NATIONALLICENCE 700 1- Cukier Celso Department of Gastroenterology, Faculty of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, 01246-903, São Paulo, SP, Brazil, BR aut NATIONALLICENCE 700 1- Santoro Sérgio Department of Gastroenterology, Faculty of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, 01246-903, São Paulo, SP, Brazil, BR aut NATIONALLICENCE 700 1- Martins Juliana R. Faculty of Medicine, University of São Paulo, Al. Franca 555, 01422-010 São Paulo, SP, Brazil, BR aut NATIONALLICENCE 700 1- Song Rubens J. Faculty of Medicine, University of São Paulo, Al. Franca 555, 01422-010 São Paulo, SP, Brazil, BR aut NATIONALLICENCE 700 1- Gama-Rodrigues Joaquim Department of Gastroenterology, Faculty of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, 01246-903, São Paulo, SP, Brazil, BR aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/12(2000-12-01), 1537-1541 0364-2313 24:12<1537 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer