caa a22 4500 475802551 CHVBK 20180406123741.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s002680010203 doi (NATIONALLICENCE)springer-10.1007/s002680010203 Kumon Hiromi Department of Urology, Okayama University Medical School, 2-5-1 Shikata, Okayama 700-8558, Japan, JP aut Management of Biofilm Infections in the Urinary Tract [Elektronische Daten] [Hiromi Kumon] Abstract : Bacterial biofilms develop on a number of living and inert surfaces within the urinary tract, producing chronic intractable infections. The role of exopolysaccharides in producing a variety of extracellular polymeric substances according to the infection site and bacterial species and the clinical features of the resulting biofilm infections were reviewed. Although fluoroquinolone shows a considerable killing effect against bacterial biofilm, no commercially available drugs are sufficiently active against the cells in a mature biofilm. Combination therapy of fluoroquinolone and macrolide or fluoroquinolone and fosfomycin may be the most effective regimen available at present. Nevertheless, management of the local urinary condition and removal of the local underlying disease are the most effective approaches to treating urinary biofilm infection. by Société Internationale de Chirurgie, 2000 World Journal of Surgery Springer-Verlag 24/10(2000-10-01), 1193-1196 0364-2313 24:10<1193 2000 24 268 https://doi.org/10.1007/s002680010203 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002680010203 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Kumon Hiromi Department of Urology, Okayama University Medical School, 2-5-1 Shikata, Okayama 700-8558, Japan, JP aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/10(2000-10-01), 1193-1196 0364-2313 24:10<1193 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer