caa a22 4500 475802624 CHVBK 20180406123741.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s002680010207 doi (NATIONALLICENCE)springer-10.1007/s002680010207 Droller Michael J. Department of Urology, Box 1272, The Mount Sinai School of Medicine, 5th Avenue and E. 100th Street, New York, New York 10029-6574, USA, US aut Urology in the Twenty-first Century: Noninvasive TargetedTreatments for Urologic Malignancies [Elektronische Daten] [Michael J. Droller] Abstract : Notwithstanding the major advances that have been made in the treatment of bladder cancer, prostate cancer, and kidney cancer, much remains to be done if we are to translate the gains that have been made in "disease-free survival" into actual survival in terms of quantity as well as quality of life. Indeed, we are still at an embryonic stage in understanding how cancers originate, whether defense mechanisms exist that can recognize these cancers and recognize them when they first develop, when cancers metastasize during their development, whether we have methods that are sufficiently accurate to distinguish between organ-confined and regional extension or spread of disease, and the means by which we can identify cancers that are likely to remain organ-confined and distinguish them from those that are predestined to metastasize. If we are to be successful in the assessment and treatment of various urologic cancers, these questions must be answered. Many new methods of assessment and treatment are being explored that in themselves may provide some answers. The present discussion focuses on these issues, on how they may lead to further understanding of the unique biology of many of these tumors, and what we may expect in terms of increased longevity and improved quality of life as we attempt to cure patients of their disease. by Société Internationale de Chirurgie, 2000 World Journal of Surgery Springer-Verlag 24/10(2000-10-01), 1211-1214 0364-2313 24:10<1211 2000 24 268 https://doi.org/10.1007/s002680010207 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002680010207 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Droller Michael J. Department of Urology, Box 1272, The Mount Sinai School of Medicine, 5th Avenue and E. 100th Street, New York, New York 10029-6574, USA, US aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/10(2000-10-01), 1211-1214 0364-2313 24:10<1211 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer