caa a22 4500 475803302 CHVBK 20180406123743.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s002689910097 doi (NATIONALLICENCE)springer-10.1007/s002689910097 Early Gastric Cancer: Unrecognized Indicator of Multiple Malignancies [Elektronische Daten] [Federico Bozzetti, Giuliano Bonfanti, Luigi Mariani, Rosalba Miceli, Salvatore Andreola] Abstract.: The aim of this study was to evaluate the postoperative outcome and occurrence of second primary malignancies in patients who underwent radical resection for early gastric cancer. Altogether 105 patients with early gastric cancer underwent radical resection and were followed up for a median period of 71 months. Overall lethality was analyzed with regard to mortality due to gastric cancer or other causes. Standardized mortality and morbidity ratios were calculated using data from the Tumor Registry of Lombardy. The 5-year survival rate was 82.8% (operative mortality excluded), which was not different from that expected from an age- and sex-matched Italian population. Ten second primary malignancies were identified, giving a standardized mortality ratio of 1.12 and a standardized morbidity ratio of 1.50. Patients undergoing surgery for early gastric cancer (especially the intestinal type) may have a circa 50% higher risk of a second tumor and should be periodically checked for other tumors, mainly in the supramesocolic area. 2000 by the Société Internationale de Chir, 2000 Bozzetti Federico Division of Surgery of the Gastrointestinal Tract, Istituto Nazionale di Tumori, Via Venezian 1, 20133 Milan, Italy, IT aut Bonfanti Giuliano Division of Surgery of the Gastrointestinal Tract, Istituto Nazionale di Tumori, Via Venezian 1, 20133 Milan, Italy, IT aut Mariani Luigi Division of Medical Statistics and Biometry, Istituto Nazionale di Tumori, Via Venezian 1, 20133 Milan, Italy, IT aut Miceli Rosalba Division of Medical Statistics and Biometry, Istituto Nazionale di Tumori, Via Venezian 1, 20133 Milan, Italy, IT aut Andreola Salvatore Division of Pathology, Istituto Nazionale di Tumori, Via Venezian 1, 20133 Milan, Italy, IT aut World Journal of Surgery Springer-Verlag 24/5(2000-05-01), 583-587 0364-2313 24:5<583 2000 24 268 https://doi.org/10.1007/s002689910097 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689910097 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bozzetti Federico Division of Surgery of the Gastrointestinal Tract, Istituto Nazionale di Tumori, Via Venezian 1, 20133 Milan, Italy, IT aut NATIONALLICENCE 700 1- Bonfanti Giuliano Division of Surgery of the Gastrointestinal Tract, Istituto Nazionale di Tumori, Via Venezian 1, 20133 Milan, Italy, IT aut NATIONALLICENCE 700 1- Mariani Luigi Division of Medical Statistics and Biometry, Istituto Nazionale di Tumori, Via Venezian 1, 20133 Milan, Italy, IT aut NATIONALLICENCE 700 1- Miceli Rosalba Division of Medical Statistics and Biometry, Istituto Nazionale di Tumori, Via Venezian 1, 20133 Milan, Italy, IT aut NATIONALLICENCE 700 1- Andreola Salvatore Division of Pathology, Istituto Nazionale di Tumori, Via Venezian 1, 20133 Milan, Italy, IT aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/5(2000-05-01), 583-587 0364-2313 24:5<583 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer