caa a22 4500 47580337X CHVBK 20180406123743.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s002689910088 doi (NATIONALLICENCE)springer-10.1007/s002689910088 Axillary Lymph Nodes in Breast Cancer: Is Size Related to Metastatic Involvement? [Elektronische Daten] [Reinhard Obwegeser, Katharina Lorenz, Maria Hohlagschwandtner, Klaus Czerwenka, Barbara Schneider, Ernst Kubista] Abstract.: Usually when using imaging procedures, such as axillary mammography or ultrasonography, a cutoff level of 5 mm for lymph node size is postulated to be not only the limit of lymph node visibility but also a sign of metastatic involvement. The aim of this study was to evaluate whether this assumption, used as a basic hypothesis in many reports, is true. A series of 72 axillary specimens from 71 breast carcinoma patients operated at the university hospital of Vienna were analyzed. A comparison of histologically noninvolved axillary specimens with those showing metastatic involvement revealed that the two groups did not differ significantly according to the number or size of lymph nodes per axilla. For lymph nodes <5 mm the probability of being metastatically involved was still 10%. Enlarged lymph nodes (5-20 mm) had a slightly higher risk of being malignant (20%). In contrast, the probability of metastatic involvement for lymph nodes >20 mm was only 40%. We suggest that many reports dealing with the prediction of malignancy in axillary lymph nodes may have used misleading basic assumptions, so the results of these studies must be viewed critically. 2000 by the Société Internationale de Chir, 2000 Obwegeser Reinhard Department of Obstetrics and Gynecology, Division of Special Gynecology, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut Lorenz Katharina Department of Obstetrics and Gynecology, Division of Special Gynecology, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut Hohlagschwandtner Maria Department of Obstetrics and Gynecology, Division of Special Gynecology, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut Czerwenka Klaus Department of Pathology, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut Schneider Barbara Department of Medical Statistics, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut Kubista Ernst Department of Obstetrics and Gynecology, Division of Special Gynecology, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut World Journal of Surgery Springer-Verlag 24/5(2000-05-01), 546-550 0364-2313 24:5<546 2000 24 268 https://doi.org/10.1007/s002689910088 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689910088 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Obwegeser Reinhard Department of Obstetrics and Gynecology, Division of Special Gynecology, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut NATIONALLICENCE 700 1- Lorenz Katharina Department of Obstetrics and Gynecology, Division of Special Gynecology, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut NATIONALLICENCE 700 1- Hohlagschwandtner Maria Department of Obstetrics and Gynecology, Division of Special Gynecology, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut NATIONALLICENCE 700 1- Czerwenka Klaus Department of Pathology, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut NATIONALLICENCE 700 1- Schneider Barbara Department of Medical Statistics, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut NATIONALLICENCE 700 1- Kubista Ernst Department of Obstetrics and Gynecology, Division of Special Gynecology, Vienna University Hospital, University of Vienna, Währingergürtel 18-20, A-1090 Vienna, Austria, AT aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 24/5(2000-05-01), 546-550 0364-2313 24:5<546 2000 24 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer