caa a22 4500 475811410 CHVBK 20180406123800.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s001920070040 doi (NATIONALLICENCE)springer-10.1007/s001920070040 Leak-Point Pressure: Clinical Application of Values at Two Different Volumes [Elektronische Daten] [M. T. McLennan, C. F. Melick, A. E. Bent] Abstract:: A prospective analysis of 306 consecutive patients with genuine stress incontinence was performed to evaluate the clinical usefulness of additional leak-point pressure (LPP) determination at 200 ml. LPP values at both volumes were compared to maximal urethral closure pressure (MUCP) in an attempt to determine a critical cut-off value for the detection of a low MUCP (≤20 cmH2O). A positive LPP at 150 ml was found in 157 patients. The mean LPP for patients with a low MUCP was 58.5 cmH2O compared to 71.6 for those with a normal MUCP, which was statistically significant (p = 0.01). The correlation coefficient between LPP and MUCP was 0.317. A negative LPP was found in 30% (24/79) of the total having a low MUCP. The addition of values for LPP at 200 ml resulted in an increase in the number who leaked to 191, a 50% increase in the detection rate of low MUCP and a statistically significant relationship between LPP ≤60 cmH2O and low MUCP. Various critical cut-off values for LPP demonstrated good specificity but poor sensitivity for the detection of a low MUCP. It was concluded that there was a statistically significant relationship between LPP and MUCP. Performing LPP at 200 ml provides additional clinically useful diagnostic information. Springer-Verlag London Limited, 2000 Key words: Leak-point pressure - Low maximal urethral closure pressure nationallicence McLennan M. T. Greater Baltimore Medical Center, Baltimore, Maryland, USA, US aut Melick C. F. Greater Baltimore Medical Center, Baltimore, Maryland, USA, US aut Bent A. E. Greater Baltimore Medical Center, Baltimore, Maryland, USA, US aut https://doi.org/10.1007/s001920070040 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s001920070040 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- McLennan M. T. Greater Baltimore Medical Center, Baltimore, Maryland, USA, US aut NATIONALLICENCE 700 1- Melick C. F. Greater Baltimore Medical Center, Baltimore, Maryland, USA, US aut NATIONALLICENCE 700 1- Bent A. E. Greater Baltimore Medical Center, Baltimore, Maryland, USA, US aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer