caa a22 4500 475811445 CHVBK 20180406123800.0 cr unu---uuuuu 170329e20000801xx s 000 0 eng 10.1007/PL00004026 doi (NATIONALLICENCE)springer-10.1007/PL00004026 Bacterial Vaginosis Increases in Pessary Users [Elektronische Daten] [B. Alnaif, H. P. Drutz] Abstract:: The purpose of this study was to examine the association between pessary use, smoking and changes in the vaginal flora. Patients using pessaries were age matched with non-pessary using controls. All candidates examined were women attending the Mount Sinai Hospital, Toronto, for genitourinary problems. Vaginal cultures were routinely performed on all women attending the unit, irrespective of symptoms. Forty-four pessary users were age matched with 176 controls (4 controls per case). The mean age was 60.1 ± 12.6 years, and 15% of these were premenopausal. The duration of pessary use ranged from 0.5 to 8 years (mean 3.3 ± 1.7). Weight, parity, smoking status, diabetes mellitus, thyroid disease, UTI and postvoid residual urine volume were not significantly different between pessary users and controls. Bacterial vaginosis (BV) was noted in 32% of pessary users, versus 10% of controls. The relative risk of developing BV in pessary users was 3.3 (OR, 4.37; 95% CI, 2.15-9.32), P= 0.0002. Smoking independently affected the vaginal flora, increasing the relative risk of developing BV to 2.9 (OR, 3.78; 95% CI, 2.05-8.25), P = 0.0013. It was concluded that pessary use is a very effective and conservative method for the treatment of genital prolapse. However, we found that the presence of a foreign body was associated with changes in the vaginal flora, thereby increasing the odds of developing bacterial vaginosis to 4.37; this was further compounded by smoking. Springer-Verlag London Limited, 2000 Key words:Bacterial vaginosis - Historical cohort study - Pessary - Smoking nationallicence Alnaif B. Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia, USA, US aut Drutz H. P. University of Toronto, Mount Sinai Hospital, Toronto, Ontario, Canada, CA aut https://doi.org/10.1007/PL00004026 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/PL00004026 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Alnaif B. Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia, USA, US aut NATIONALLICENCE 700 1- Drutz H. P. University of Toronto, Mount Sinai Hospital, Toronto, Ontario, Canada, CA aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer