caa a22 4500 475817818 CHVBK 20180406123813.0 cr unu---uuuuu 170329e20000101xx s 000 0 eng 10.1007/s002280050012 doi (NATIONALLICENCE)springer-10.1007/s002280050012 Drug utilisation in Dutch nursing homes [Elektronische Daten] [K. N. van Dijk, C. S. de Vries, P. B. van den Berg, J. R. B. J Brouwers, L. T. W. de Jong-van den Berg] Objective: To quantify and evaluate drug utilisation in a sample of Dutch nursing homes. Methods: A retrospective analysis of computerised medication data of 2355 residents aged 65 years and over from six nursing homes in the Netherlands was performed. For each therapeutic drug group, the number of users was determined. The ten therapeutic groups used most frequently were investigated further. For these, patient characteristics, use of therapeutic subgroups, the average daily dosages and the chronicity of drug use were determined. Chronicity was expressed as the percentage of treatment days divided by the number of residents' days in the nursing home. Results: During the study period, 89%, 77% and 56% of the study population used a drug from the anatomical therapeutic chemical (ATC) main group N (nervous system), A (alimentary tract and metabolism) and C (cardiovascular system), respectively. Eight of the ten therapeutic drug groups prescribed most frequently were used for more than 50% of the time. In particular, psycholeptic drugs, diuretics and laxatives were used chronically (83%, 81%, and 80% of the nursing home stay, respectively). Except for a few drug groups, such as laxatives and diuretics, the prescribed daily dosages were relatively low. Twenty-eight percent of the residents received loop diuretics; these were prescribed in relatively high dosages. Conclusion: Drug utilisation in the nursing homes was high and many drugs were used chronically. In view of the risk of possible adverse effects and drug-drug interactions, the prescribing and dosage of psycholeptic drugs, laxatives, loop diuretics and ulcer-healing drugs should be re-evaluated, carefully. Springer-Verlag Berlin Heidelberg, 2000 Key words Nursing home nationallicence Drug utilisation nationallicence Elderly nationallicence van Dijk K. N. Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen Institute for Drug Studies (GIDS), A. Deusinglaan 2, 9713 AW Groningen, The Netherlands e-mail: lolkje@farm.rug.nl Tel.: +31-50-3633330; Fax: +31-50-3633311, NL aut de Vries C. S. Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen Institute for Drug Studies (GIDS), A. Deusinglaan 2, 9713 AW Groningen, The Netherlands e-mail: lolkje@farm.rug.nl Tel.: +31-50-3633330; Fax: +31-50-3633311, NL aut van den Berg P. B. Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen Institute for Drug Studies (GIDS), A. Deusinglaan 2, 9713 AW Groningen, The Netherlands e-mail: lolkje@farm.rug.nl Tel.: +31-50-3633330; Fax: +31-50-3633311, NL aut Brouwers J. R. B. J. Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen Institute for Drug Studies (GIDS), A. Deusinglaan 2, 9713 AW Groningen, The Netherlands e-mail: lolkje@farm.rug.nl Tel.: +31-50-3633330; Fax: +31-50-3633311, NL aut de Jong-van den Berg L. T. W. Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen Institute for Drug Studies (GIDS), A. Deusinglaan 2, 9713 AW Groningen, The Netherlands e-mail: lolkje@farm.rug.nl Tel.: +31-50-3633330; Fax: +31-50-3633311, NL aut https://doi.org/10.1007/s002280050012 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002280050012 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- van Dijk K. N. Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen Institute for Drug Studies (GIDS), A. Deusinglaan 2, 9713 AW Groningen, The Netherlands e-mail: lolkje@farm.rug.nl Tel.: +31-50-3633330; Fax: +31-50-3633311, NL aut NATIONALLICENCE 700 1- de Vries C. S. Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen Institute for Drug Studies (GIDS), A. Deusinglaan 2, 9713 AW Groningen, The Netherlands e-mail: lolkje@farm.rug.nl Tel.: +31-50-3633330; Fax: +31-50-3633311, NL aut NATIONALLICENCE 700 1- van den Berg P. B. Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen Institute for Drug Studies (GIDS), A. Deusinglaan 2, 9713 AW Groningen, The Netherlands e-mail: lolkje@farm.rug.nl Tel.: +31-50-3633330; Fax: +31-50-3633311, NL aut NATIONALLICENCE 700 1- Brouwers J. R. B. J. Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen Institute for Drug Studies (GIDS), A. Deusinglaan 2, 9713 AW Groningen, The Netherlands e-mail: lolkje@farm.rug.nl Tel.: +31-50-3633330; Fax: +31-50-3633311, NL aut NATIONALLICENCE 700 1- de Jong-van den Berg L. T. W. Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen Institute for Drug Studies (GIDS), A. Deusinglaan 2, 9713 AW Groningen, The Netherlands e-mail: lolkje@farm.rug.nl Tel.: +31-50-3633330; Fax: +31-50-3633311, NL aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer