caa a22 4500 475818180 CHVBK 20180406123814.0 cr unu---uuuuu 170329e20000401xx s 000 0 eng 10.1007/s002280050727 doi (NATIONALLICENCE)springer-10.1007/s002280050727 Antibiotic utilization at the university hospital after introducing an antibiotic policy [Elektronische Daten] [V. Vlahovic-Palcevski, M. Morovic, G. Palcevski] Objective: Antibiotic formulary restrictions are among the most popular methods to control antibiotic utilization in hospitals. The aim of the present survey was to investigate the influence of "reserve antibiotic” on antimicrobial utilization at the University Hospital Center (UHC) Rijeka. Methods: At the UHC Rijeka, reserve antibiotic was implemented in July 1997. The antimicrobial drug consumption was monitored 6 months prior to and 6 months after the introduction of the method. Antimicrobial consumption was measured in defined daily doses (DDDs) among the major clinics. Results: Reserve antibiotic has led to a decrease in total antibiotic consumption at the UHC Rijeka (45.9 DDDs/100 bed days vs 32.9 DDDs/100 bed days). Antibiotic utilization decreased in the second semester at most clinics: at the Clinic for Infectious Diseases 41%, at the Anesthesiology and Intensive Care Unit 30%, at the Clinic for Internal Medicine 18% and at the Surgical Clinic 12%. At the Clinic for Gynecology and Obstetrics, the antibiotic utilization remained the same, while at the Pediatric Clinic an increase of 28% in antibiotic utilization was noted. Conclusion: Our study indicates that restriction of usage of some antibacterial agents is a successful method to decrease antibiotic consumption and a way to bring cost savings and helps prevent emergence of resistant microorganisms in hospitals. To improve antimicrobial prescribing, additional methods such as education are required. Springer-Verlag Berlin Heidelberg, 2000 Key words Antibiotics nationallicence Antimicrobial utilization nationallicence Reserve antibiotic nationallicence Vlahovic-Palcevski V. Department of Pharmacology, University of Rijeka Medical School, Brace Branchetta 20, HR-51000 Rijeka, Croatia e-mail: Vera.Vlahovic-Palcevski@mamed.medri.hr Tel.: +385-51-429858; +385-51-651189, HR aut Morovic M. Clinic for Infectious Diseases, University Hospital Center Rijeka, Croatia, HR aut Palcevski G. Pediatric Clinic, University Hospital Center Rijeka, Croatia, HR aut https://doi.org/10.1007/s002280050727 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002280050727 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vlahovic-Palcevski V. Department of Pharmacology, University of Rijeka Medical School, Brace Branchetta 20, HR-51000 Rijeka, Croatia e-mail: Vera.Vlahovic-Palcevski@mamed.medri.hr Tel.: +385-51-429858; +385-51-651189, HR aut NATIONALLICENCE 700 1- Morovic M. Clinic for Infectious Diseases, University Hospital Center Rijeka, Croatia, HR aut NATIONALLICENCE 700 1- Palcevski G. Pediatric Clinic, University Hospital Center Rijeka, Croatia, HR aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer