caa a22 4500 475818784 CHVBK 20180406123816.0 cr unu---uuuuu 170329e20001101xx s 000 0 eng 10.1007/s002280000199 doi (NATIONALLICENCE)springer-10.1007/s002280000199 Corticosteroid therapy and need for hospital care in wheezing preschool children [Elektronische Daten] [Péter Csonka, Jussi Mertsola, Timo Klaukka, Minna Kaila, Marja-Riitta Ståhlberg, Per Ashorn] Abstract.: Objectives: To study the frequency of corticosteroid therapy and the use of inpatient care for preschool children with wheezing in two regions in Finland. Methods: The Finnish Social Insurance Institution database on refundable asthma medication indicated that 1.18% of children in Tampere and 2.37% in Turku used inhaled corticosteroids regularly. To clarify the difference, hospital records of 800 randomly chosen 0.5-6.9-year-old children who had been treated for wheezing in Tampere or Turku University Hospital during 1995-1996 were retrospectively analysed. Results: The incidences of wheezing-related emergency room (ER) index visits were 11.0 visits/year/1000children both in Tampere and Turku. Oral corticosteroids were given to 2.5% versus 24.2% of children in ER and 10.6% versus 89.7% in hospital ward in Tampere and Turku, respectively. Hospitalisation rates were 44.8% in Tampere and 36.8% in Turku (95% confidence interval for the difference 1.2-14.8%). In both regions, children with prior inhaled corticosteroid therapy needed less inpatient care. Mean duration of hospitalisation was 3.4days in Tampere and only 1.4days in Turku. Recurrent visits in 6months were more common in Tampere. Conclusions: There were marked regional differences in the management of preschool children with wheezing. On a population level, frequent use of corticosteroid therapy was associated with reduced hospital admissions. Springer-Verlag, 2000 Anti-inflammatory therapy Corticosteroids Preschool children nationallicence Csonka Péter University of Tampere, Medical School, P.O. Box 607, FIN-33101, Tampere, Finland aut Mertsola Jussi Turku University Hospital, Turku, Finland, Turku, Finland aut Klaukka Timo The Social Insurance Institution, Helsinki, Finland, Helsinki, Finland aut Kaila Minna University of Tampere, Medical School, P.O. Box 607, FIN-33101, Tampere, Finland aut Ståhlberg Marja-Riitta Turku University Hospital, Turku, Finland, Turku, Finland aut Ashorn Per University of Tampere, Medical School, P.O. Box 607, FIN-33101, Tampere, Finland aut European Journal of Clinical Pharmacology Springer-Verlag 56/8(2000-11-01), 591-596 0031-6970 56:8<591 2000 56 228 https://doi.org/10.1007/s002280000199 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002280000199 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Csonka Péter University of Tampere, Medical School, P.O. Box 607, FIN-33101, Tampere, Finland aut NATIONALLICENCE 700 1- Mertsola Jussi Turku University Hospital, Turku, Finland, Turku, Finland aut NATIONALLICENCE 700 1- Klaukka Timo The Social Insurance Institution, Helsinki, Finland, Helsinki, Finland aut NATIONALLICENCE 700 1- Kaila Minna University of Tampere, Medical School, P.O. Box 607, FIN-33101, Tampere, Finland aut NATIONALLICENCE 700 1- Ståhlberg Marja-Riitta Turku University Hospital, Turku, Finland, Turku, Finland aut NATIONALLICENCE 700 1- Ashorn Per University of Tampere, Medical School, P.O. Box 607, FIN-33101, Tampere, Finland aut NATIONALLICENCE 773 0- European Journal of Clinical Pharmacology Springer-Verlag 56/8(2000-11-01), 591-596 0031-6970 56:8<591 2000 56 228 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer