caa a22 4500 475824148 CHVBK 20180406123826.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1023/A:1018712520472 doi (NATIONALLICENCE)springer-10.1023/A:1018712520472 INR Self-Management Following Mechanical Heart Valve Replacement [Elektronische Daten] [Heinrich Koertke, Kazutomo Minami, Andreas Bairaktaris, Otto Wagner, Reiner Koerfer] INR self-management can reduce severe thromboembolic and hemorrhagic complications following mechanical heart valve replacement. Beginning anticoagulation therapy immediately in the postoperative period further reduces anticoagulant-induced complications. Data were collected from the first 600 surviving patients (from a total study sample of 1200 patients) who completed follow-up of at least 2 years. Patients were randomly divided into a self-management group and a control group. INR self-management reduced severe hemorrhagic and thromboembolic complications (P=0.018). Nearly 80% of INR values recorded by patients themselves, regardless of educational level, were within the target therapeutic range of INR 2.5-4.5, compared with 62% of INR values monitored by family practitioners. Only 8.3% of patients trained in self-management immediately after surgery were unable to continue with INR self-management. The results differed slightly between patient groups with different levels of education. We conclude that all patients for whom anticoagulation is indicated are candidates for INR self-management regardless of education level. Kluwer Academic Publishers, 2000 anticoagulation nationallicence heart valve replacement nationallicence INR self-management nationallicence patient compliance nationallicence education level nationallicence Koertke Heinrich Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany aut Minami Kazutomo Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany aut Bairaktaris Andreas Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany aut Wagner Otto Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany aut Koerfer Reiner Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany aut Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 9(2000-06-01), 41-45 0929-5305 9<41 2000 9 11239 https://doi.org/10.1023/A:1018712520472 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018712520472 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Koertke Heinrich Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany aut NATIONALLICENCE 700 1- Minami Kazutomo Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany aut NATIONALLICENCE 700 1- Bairaktaris Andreas Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany aut NATIONALLICENCE 700 1- Wagner Otto Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany aut NATIONALLICENCE 700 1- Koerfer Reiner Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany aut NATIONALLICENCE 773 0- Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 9(2000-06-01), 41-45 0929-5305 9<41 2000 9 11239 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer