caa a22 4500 475824164 CHVBK 20180406123826.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1023/A:1018722001817 doi (NATIONALLICENCE)springer-10.1023/A:1018722001817 Community Impact of Anticoagulation Services: Rationale and Design of the Managing Anticoagulation Services Trial (MAST) [Elektronische Daten] [David Matchar, Gregory Samsa, Stuart Cohen, Eugene Oddone] We describe the design of the Managing Anti-coagulation Services Trial (MAST), a practice-improvement trial testing whether anticoagulation services are a preferred method of managing anticoagulation for stroke prevention among patients with atrial fibrillation. Most randomized trials within the health care environment are designed as efficacy studies to determine what works under ideal conditions or ideal clinical practice. In contrast, effectiveness trials seek to generalize the results of efficacy studies by determining what works under more typical practice conditions. Practice-improvement trials are effectiveness trials that examine the management of a clinical problem in the context in which care is usually given. Noteworthy features of the MAST include defining the intervention in functional terms and collaboration with managed care organizations. Kluwer Academic Publishers, 2000 stroke prevention nationallicence anticoagulation service nationallicence randomized trial nationallicence effectiveness trial nationallicence design nationallicence managed care organization nationallicence Matchar David Center for Clinical Health Policy Research, Duke University Medical Center, Durham, North Carolina aut Samsa Gregory Center for Clinical Health Policy Research, Duke University Medical Center, Durham, North Carolina aut Cohen Stuart The University of Arizona Prevention Center, Tucson, Arizona aut Oddone Eugene Center for Clinical Health Policy Research, Duke University Medical Center, Durham, North Carolina aut Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 9(2000-06-01), 7-11 0929-5305 9<7 2000 9 11239 https://doi.org/10.1023/A:1018722001817 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018722001817 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Matchar David Center for Clinical Health Policy Research, Duke University Medical Center, Durham, North Carolina aut NATIONALLICENCE 700 1- Samsa Gregory Center for Clinical Health Policy Research, Duke University Medical Center, Durham, North Carolina aut NATIONALLICENCE 700 1- Cohen Stuart The University of Arizona Prevention Center, Tucson, Arizona aut NATIONALLICENCE 700 1- Oddone Eugene Center for Clinical Health Policy Research, Duke University Medical Center, Durham, North Carolina aut NATIONALLICENCE 773 0- Journal of Thrombosis and Thrombolysis Kluwer Academic Publishers 9(2000-06-01), 7-11 0929-5305 9<7 2000 9 11239 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer